| Round 1 (22) | Round 2 (23) |
| Bayern München - Strasbourg | Ajax - FC Schalke 04 |
| Boca Juniors - Chelsea | Aston Villa - Boca Juniors |
| FC Schalke 04 - FC Porto | Barcelona - Feyenoord |
| Feyenoord - Marseille | Bayer Leverkusen - Bayern München |
| Independiente - Ajax | Borussia Dortmund - Lyon |
| Liverpool - Manchester City | Chelsea - Napoli |
| Lyon - Aston Villa | FC Porto - Independiente |
| Napoli - Bayer Leverkusen | Flamengo - Sporting Braga |
| Real Madrid - Flamengo | Manchester City - West Ham United |
| Sporting Braga - Borussia Dortmund | Marseille - Liverpool |
| West Ham United - Barcelona | Strasbourg - Real Madrid |
|
| Round 3 (24) | Round 4 (25) |
| Bayern München - Chelsea | Ajax - Napoli |
| Boca Juniors - FC Porto | Aston Villa - Real Madrid |
| FC Schalke 04 - Barcelona | Barcelona - Liverpool |
| Feyenoord - Strasbourg | Bayer Leverkusen - Lyon |
| Independiente - Flamengo | Borussia Dortmund - Feyenoord |
| Liverpool - Ajax | Chelsea - Sporting Braga |
| Lyon - Marseille | FC Porto - West Ham United |
| Napoli - Aston Villa | Flamengo - FC Schalke 04 |
| Real Madrid - Bayer Leverkusen | Manchester City - Independiente |
| Sporting Braga - Manchester City | Marseille - Bayern München |
| West Ham United - Borussia Dortmund | Strasbourg - Boca Juniors |
|
| Round 5 (26) | Round 6 (27) |
| Bayern München - FC Porto | Barcelona - FC Porto |
| Boca Juniors - Barcelona | Bayer Leverkusen - Aston Villa |
| FC Schalke 04 - Borussia Dortmund | Bayern München - Napoli |
| Feyenoord - Bayer Leverkusen | Boca Juniors - Ajax |
| Independiente - Marseille | Borussia Dortmund - Marseille |
| Liverpool - Aston Villa | Chelsea - Strasbourg |
| Lyon - Ajax | Feyenoord - Real Madrid |
| Napoli - Manchester City | Flamengo - Manchester City |
| Real Madrid - Chelsea | Independiente - West Ham United |
| Sporting Braga - Strasbourg | Liverpool - FC Schalke 04 |
| West Ham United - Flamengo | Lyon - Sporting Braga |
|
| Round 7 (28) | Round 8 (29) |
| Ajax - Barcelona | Aston Villa - West Ham United |
| Aston Villa - Chelsea | Barcelona - Strasbourg |
| FC Porto - Borussia Dortmund | Boca Juniors - Napoli |
| FC Schalke 04 - Independiente | Chelsea - Bayer Leverkusen |
| Manchester City - Boca Juniors | FC Porto - Ajax |
| Marseille - Flamengo | FC Schalke 04 - Real Madrid |
| Napoli - Feyenoord | Flamengo - Borussia Dortmund |
| Real Madrid - Lyon | Independiente - Liverpool |
| Sporting Braga - Bayern München | Lyon - Bayern München |
| Strasbourg - Bayer Leverkusen | Manchester City - Marseille |
| West Ham United - Liverpool | Sporting Braga - Feyenoord |
|
| Round 9 (30) | Round 10 (31) |
| Ajax - Chelsea | Ajax - Real Madrid |
| Bayer Leverkusen - Barcelona | Barcelona - Chelsea |
| Bayern München - Boca Juniors | Borussia Dortmund - Napoli |
| Borussia Dortmund - Manchester City | FC Porto - Bayer Leverkusen |
| Feyenoord - Lyon | FC Schalke 04 - Bayern München |
| Liverpool - Flamengo | Flamengo - Boca Juniors |
| Marseille - FC Porto | Independiente - Sporting Braga |
| Napoli - Independiente | Liverpool - Feyenoord |
| Real Madrid - Sporting Braga | Manchester City - Aston Villa |
| Strasbourg - Aston Villa | Marseille - Strasbourg |
| West Ham United - FC Schalke 04 | West Ham United - Lyon |
|
| Round 11 (32) | Round 12 (33) |
| Aston Villa - FC Porto | Aston Villa - Marseille |
| Bayer Leverkusen - Marseille | Bayer Leverkusen - Manchester City |
| Bayern München - Manchester City | Bayern München - Ajax |
| Boca Juniors - FC Schalke 04 | Boca Juniors - Borussia Dortmund |
| Chelsea - Independiente | Chelsea - FC Schalke 04 |
| Feyenoord - West Ham United | Feyenoord - Independiente |
| Lyon - Barcelona | Lyon - Liverpool |
| Napoli - Flamengo | Napoli - Barcelona |
| Real Madrid - Liverpool | Real Madrid - West Ham United |
| Sporting Braga - Ajax | Sporting Braga - FC Porto |
| Strasbourg - Borussia Dortmund | Strasbourg - Flamengo |
|
| Round 13 (34) | Round 14 (35) |
| Ajax - Aston Villa | Aston Villa - Flamengo |
| Barcelona - Sporting Braga | Bayer Leverkusen - Ajax |
| Borussia Dortmund - Chelsea | Bayern München - Borussia Dortmund |
| FC Porto - Feyenoord | Boca Juniors - Independiente |
| FC Schalke 04 - Lyon | Chelsea - Marseille |
| Flamengo - Bayer Leverkusen | Feyenoord - Manchester City |
| Independiente - Real Madrid | Lyon - FC Porto |
| Liverpool - Bayern München | Napoli - Liverpool |
| Manchester City - Strasbourg | Real Madrid - Barcelona |
| Marseille - Napoli | Sporting Braga - West Ham United |
| West Ham United - Boca Juniors | Strasbourg - FC Schalke 04 |
|
| Round 15 (36) | Round 16 (37) |
| Ajax - Strasbourg | Aston Villa - Borussia Dortmund |
| Barcelona - Aston Villa | Bayer Leverkusen - Independiente |
| Borussia Dortmund - Bayer Leverkusen | Bayern München - Barcelona |
| FC Porto - Real Madrid | Boca Juniors - Liverpool |
| FC Schalke 04 - Feyenoord | Chelsea - Flamengo |
| Flamengo - Bayern München | Feyenoord - Ajax |
| Independiente - Lyon | Lyon - Manchester City |
| Liverpool - Sporting Braga | Napoli - FC Porto |
| Manchester City - Chelsea | Real Madrid - Marseille |
| Marseille - Boca Juniors | Sporting Braga - FC Schalke 04 |
| West Ham United - Napoli | Strasbourg - West Ham United |
|
| Round 17 (38) | Round 18 (39) |
| Bayern München - Aston Villa | Ajax - Flamengo |
| Boca Juniors - Bayer Leverkusen | Barcelona - Borussia Dortmund |
| FC Schalke 04 - Manchester City | FC Porto - Chelsea |
| Feyenoord - Chelsea | FC Schalke 04 - Napoli |
| Independiente - Barcelona | Feyenoord - Boca Juniors |
| Liverpool - FC Porto | Independiente - Bayern München |
| Lyon - Flamengo | Liverpool - Bayer Leverkusen |
| Napoli - Strasbourg | Lyon - Strasbourg |
| Real Madrid - Borussia Dortmund | Real Madrid - Manchester City |
| Sporting Braga - Marseille | Sporting Braga - Aston Villa |
| West Ham United - Ajax | West Ham United - Marseille |
|
| Round 19 (40) | Round 20 (41) |
| Aston Villa - Independiente | Ajax - Manchester City |
| Bayer Leverkusen - Sporting Braga | Barcelona - Marseille |
| Bayern München - West Ham United | FC Porto - Flamengo |
| Boca Juniors - Lyon | FC Schalke 04 - Aston Villa |
| Borussia Dortmund - Ajax | Feyenoord - Bayern München |
| Chelsea - Liverpool | Independiente - Strasbourg |
| Flamengo - Feyenoord | Liverpool - Borussia Dortmund |
| Manchester City - Barcelona | Lyon - Chelsea |
| Marseille - FC Schalke 04 | Real Madrid - Boca Juniors |
| Napoli - Real Madrid | Sporting Braga - Napoli |
| Strasbourg - FC Porto | West Ham United - Bayer Leverkusen |
|
| Round 21 (42) |
| Aston Villa - Feyenoord |
| Bayer Leverkusen - FC Schalke 04 |
| Bayern München - Real Madrid |
| Boca Juniors - Sporting Braga |
| Borussia Dortmund - Independiente |
| Chelsea - West Ham United |
| Flamengo - Barcelona |
| Manchester City - FC Porto |
| Marseille - Ajax |
| Napoli - Lyon |
| Strasbourg - Liverpool |
League rounds 22-42 (in brackets) are the respective return ties of rounds 1-21 above,
ie. round 42 is Ajax - Marseille, Barcelona - Flamengo etc. |