| Round 1 (22) | Round 2 (23) |
| Anderlecht - Athletic Bilbao | AEK - Rangers |
| Arsenal - Deportivo | Athletic Bilbao - Boca Juniors |
| Boca Juniors - Lille | Deportivo - SC Heerenveen |
| Celtic - IFK Göteborg | IFK Göteborg - FC Basel |
| FC Basel - Marseille | Lazio - Arsenal |
| Genoa - AEK | Lens - Sporting |
| Juventus - Liverpool | Lille - Anderlecht |
| Paris SG - Newcastle United | Liverpool - Genoa |
| Rangers - Lens | Marseille - Paris SG |
| SC Heerenveen - Osasuna | Newcastle United - Celtic |
| Sporting - Lazio | Osasuna - Juventus |
|
| Round 3 (24) | Round 4 (25) |
| Anderlecht - Newcastle United | AEK - Celtic |
| Arsenal - Lens | Athletic Bilbao - Paris SG |
| Boca Juniors - Liverpool | Deportivo - Rangers |
| Celtic - Osasuna | IFK Göteborg - SC Heerenveen |
| FC Basel - Lille | Lazio - Genoa |
| Genoa - Marseille | Lens - Juventus |
| Juventus - Deportivo | Lille - Arsenal |
| Paris SG - AEK | Liverpool - Anderlecht |
| Rangers - IFK Göteborg | Marseille - Boca Juniors |
| SC Heerenveen - Lazio | Newcastle United - FC Basel |
| Sporting - Athletic Bilbao | Osasuna - Sporting |
|
| Round 5 (26) | Round 6 (27) |
| Anderlecht - AEK | AEK - IFK Göteborg |
| Arsenal - Marseille | Boca Juniors - Paris SG |
| Boca Juniors - IFK Göteborg | Celtic - Juventus |
| Celtic - Deportivo | Deportivo - Lens |
| FC Basel - Lens | FC Basel - Anderlecht |
| Genoa - Osasuna | Lazio - Osasuna |
| Juventus - Lazio | Liverpool - Marseille |
| Paris SG - Liverpool | Newcastle United - Athletic Bilbao |
| Rangers - Lille | Rangers - Genoa |
| SC Heerenveen - Athletic Bilbao | SC Heerenveen - Arsenal |
| Sporting - Newcastle United | Sporting - Lille |
|
| Round 7 (28) | Round 8 (29) |
| Anderlecht - Boca Juniors | Anderlecht - Juventus |
| Arsenal - Celtic | Athletic Bilbao - Lille |
| Athletic Bilbao - AEK | Boca Juniors - FC Basel |
| Genoa - SC Heerenveen | Genoa - Celtic |
| IFK Göteborg - Liverpool | Lazio - Deportivo |
| Juventus - Rangers | Lens - Paris SG |
| Lens - Lazio | Liverpool - AEK |
| Lille - Newcastle United | Marseille - IFK Göteborg |
| Marseille - Sporting | Newcastle United - Osasuna |
| Osasuna - Deportivo | Rangers - SC Heerenveen |
| Paris SG - FC Basel | Sporting - Arsenal |
|
| Round 9 (30) | Round 10 (31) |
| AEK - Marseille | AEK - Arsenal |
| Arsenal - Boca Juniors | Anderlecht - SC Heerenveen |
| Celtic - Rangers | Athletic Bilbao - Deportivo |
| Deportivo - Newcastle United | Boca Juniors - Genoa |
| FC Basel - Liverpool | FC Basel - Celtic |
| IFK Göteborg - Athletic Bilbao | IFK Göteborg - Osasuna |
| Juventus - Genoa | Lille - Juventus |
| Lille - Lazio | Liverpool - Sporting |
| Osasuna - Lens | Marseille - Lens |
| Paris SG - Anderlecht | Newcastle United - Lazio |
| SC Heerenveen - Sporting | Paris SG - Rangers |
|
| Round 11 (32) | Round 12 (33) |
| Arsenal - Liverpool | Arsenal - Newcastle United |
| Celtic - Paris SG | Celtic - Boca Juniors |
| Deportivo - IFK Göteborg | Deportivo - Marseille |
| Genoa - Lille | Genoa - Athletic Bilbao |
| Juventus - FC Basel | Juventus - Paris SG |
| Lazio - Boca Juniors | Lazio - Anderlecht |
| Lens - Athletic Bilbao | Lens - IFK Göteborg |
| Osasuna - AEK | Osasuna - Liverpool |
| Rangers - Newcastle United | Rangers - FC Basel |
| SC Heerenveen - Marseille | SC Heerenveen - Lille |
| Sporting - Anderlecht | Sporting - AEK |
|
| Round 13 (34) | Round 14 (35) |
| AEK - Lazio | Arsenal - FC Basel |
| Anderlecht - Rangers | Celtic - Marseille |
| Athletic Bilbao - Celtic | Deportivo - Lille |
| Boca Juniors - Juventus | Genoa - Paris SG |
| FC Basel - SC Heerenveen | Juventus - Newcastle United |
| IFK Göteborg - Arsenal | Lazio - IFK Göteborg |
| Lille - Lens | Lens - Liverpool |
| Liverpool - Deportivo | Osasuna - Anderlecht |
| Marseille - Osasuna | Rangers - Athletic Bilbao |
| Newcastle United - Genoa | SC Heerenveen - AEK |
| Paris SG - Sporting | Sporting - Boca Juniors |
|
| Round 15 (36) | Round 16 (37) |
| AEK - Deportivo | Arsenal - Athletic Bilbao |
| Anderlecht - Celtic | Celtic - Lille |
| Athletic Bilbao - Juventus | Deportivo - Boca Juniors |
| Boca Juniors - Rangers | Genoa - Anderlecht |
| FC Basel - Genoa | Juventus - IFK Göteborg |
| IFK Göteborg - Sporting | Lazio - Liverpool |
| Lille - Osasuna | Lens - AEK |
| Liverpool - SC Heerenveen | Osasuna - Paris SG |
| Marseille - Lazio | Rangers - Marseille |
| Newcastle United - Lens | SC Heerenveen - Newcastle United |
| Paris SG - Arsenal | Sporting - FC Basel |
|
| Round 17 (38) | Round 18 (39) |
| Anderlecht - Marseille | Anderlecht - Arsenal |
| Arsenal - Osasuna | Athletic Bilbao - Lazio |
| Boca Juniors - Newcastle United | Boca Juniors - SC Heerenveen |
| Celtic - Lazio | Celtic - Sporting |
| FC Basel - Athletic Bilbao | FC Basel - Deportivo |
| Genoa - IFK Göteborg | Genoa - Lens |
| Juventus - AEK | Juventus - Marseille |
| Paris SG - Lille | Lille - Liverpool |
| Rangers - Liverpool | Newcastle United - AEK |
| SC Heerenveen - Lens | Paris SG - IFK Göteborg |
| Sporting - Deportivo | Rangers - Osasuna |
|
| Round 19 (40) | Round 20 (41) |
| AEK - Lille | Anderlecht - Lens |
| Arsenal - Juventus | Athletic Bilbao - Liverpool |
| Deportivo - Genoa | Boca Juniors - Osasuna |
| IFK Göteborg - Anderlecht | Celtic - SC Heerenveen |
| Lazio - FC Basel | FC Basel - AEK |
| Lens - Boca Juniors | Genoa - Arsenal |
| Liverpool - Celtic | Juventus - Sporting |
| Marseille - Newcastle United | Lille - Marseille |
| Osasuna - Athletic Bilbao | Newcastle United - IFK Göteborg |
| SC Heerenveen - Paris SG | Paris SG - Deportivo |
| Sporting - Rangers | Rangers - Lazio |
|
| Round 21 (42) |
| AEK - Boca Juniors |
| Arsenal - Rangers |
| Deportivo - Anderlecht |
| IFK Göteborg - Lille |
| Lazio - Paris SG |
| Lens - Celtic |
| Liverpool - Newcastle United |
| Marseille - Athletic Bilbao |
| Osasuna - FC Basel |
| SC Heerenveen - Juventus |
| Sporting - Genoa |
League rounds 22-42 (in brackets) are the respective return ties of rounds 1-21 above, ie. round 42 is Anderlecht - Deportivo, Athletic Bilbao - Marseille etc. |