| Round 21 | | Aston Villa | 0 |
| | Half-time: | 0-1 | | Referee: | Dowd 5½ | | Attendance: | 42,470 | | Possession: | 45%-55% | | Total shots: | 9-20 | | MoM: | Bellingham |
| | 55 Vlachodimos | | (4-3-3): Vlachodimos 6½, Boey 6½, Mendy 7, Pellegrini 7, Laporte 7, Carrasco 6½, Zaniolo 6, Di María 6, Depay 7, Rabiot 6, Mané 5½ | | Manchester City | 1 | 14 Vinícius Júnior |
| | (3-1-3-3): Ederson 6½, Bellingham 7½, Gonçalo Inácio 6½, Vinícius Júnior 7, De Bruyne 7, Rodri 7, Rúben Dias 7, Davies 6, Foden 7, Haaland 6½, Saka 6½ | | Colchester United | 2 | 15 Jota, 72 Jota | | Half-time: | 1-1 | | Referee: | Foy 6½ | | Attendance: | 24,937 | | Possession: | 51%-49% | | Total shots: | 11-17 | | MoM: | Barnes | | TV: | highlights |
| | 6 Jota | | (4-3-3): Trapp 7, Mazraoui 6 (47 Ben Yedder 8), Buchanan 5½, Barnes 8, Lindelöf 7, Huijsen 6½, Madueke 6½, Jota 7½, Højlund 6½, Kjærgaard 6, Nketiah 5½ | | Crystal Palace | 1 | 8 Vlahovic |
| | (3-5-2): Vicario 7, Yan Couto 7½, Darmian 7, Kim 8, Camavinga 7, Tonali 7, Brahim 7, Nico 7, Dani Olmo 7, Vlahovic 6½, Summerville 6 | | Leeds United | 0 |
| | Half-time: | 0-2 | | Referee: | Reed 6½ | | Attendance: | 37,746 | | Possession: | 44%-56% | | Total shots: | 10-13 | | MoM: | Hincapié | | TV: | highlights |
| | 52 Rakitic, 61 Azpilicueta | | (3-5-2): Nübel 6½, Dumfries 7, Azpilicueta 6, Rakitic 6, Bastoni 7, Nwaneri 7, Lookman 6½, Thuram 7½, Saúl 5½, Asensio 6½, Bentancur 6 | | Port Vale | 2 | 20 Openda, 36 Openda | | 3 Kudus | | (4-1-3-2): Benítez 6, Ryerson 8, Udogie 7½, Hincapié 8, White 7½, Frattesi 7½, Kudus 7½, Barcola 6½, Openda 7½, Müller 6½, Trossard 6 | | Leicester City | 2 | 11 Molina, 62 Mikel | | Half-time: | 1-1 | | Referee: | Rennie 6 | | Attendance: | 43,825 | | Possession: | 51%-49% | | Total shots: | 14-12 | | MoM: | Szoboszlai |
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| | (4-4-2): Raya 6½, Balde 7, Dimarco 7½, Locatelli 8, Mikel 7½, Pau Torres 6½, Molina 7, Gravenberch 6½, Gavi 7, Sané 5½, Martínez 7 | | Arsenal | 3 | 25 Martinelli, 60 Martinelli, 61 Martinelli | | 80 Matheus Cunha, 82 Coman, 83 Fofana | | (3-5-2): Maignan 6, Szoboszlai 8, Tah 6½, Ødegaard 6½, Saliba 7, Aké 7, Savinho 7½, Coman 6½, Matheus Cunha 6½, Fofana 6, Martinelli 7 | | Manchester United | 1 | 63 Trippier | | Half-time: | 0-0 | | Referee: | D'Urso 7 | | Attendance: | 42,665 | | Possession: | 44%-56% | | Total shots: | 15-14 | | MoM: | Greenwood | | TV: | highlights |
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| | (4-3-3): Meret 7, Trippier 7½, Martínez 6, Wieffer 7½, Stones 7, Maguire 7, Greenwood 8, Sancho 6, Diallo 6, Jensen 6, Biancheri 5½ | | Sunderland | 1 | 85 Dembélé |
| | (4-4-2): Remiro 6, Cambiaso 7½, Alex Grimaldo 7, Pedro Neto 8, Romagnoli 7, Romero 6½, Çalhanoglu 7½, Mac Allister 7, Boniface 6½, Dembélé 7, Álex Baena 6 | | Nottingham Forest | 2 | 58 Iago, 65 Kent | | Half-time: | 0-0 | | Referee: | Beeby 6½ | | Attendance: | 30,317 | | Possession: | 51%-49% | | Total shots: | 17-20 | | MoM: | Raum |
| | 85 Scamacca | | (4-3-3): Henderson 6½, Tavernier 6 (58 Dest 6), Davies 7½, Gross 7, Koulibaly 6, Niakhaté 6, Palmer 6, Kent 6½, Scamacca 6½, Awoniyi 6, Iago 6½ | | Liverpool | 1 | 72 Salah |
| | (3-4-3): Alisson 7, Alexander-Arnold 6½, Robertson 7, Giménez 6½, Raum 8, Van Dijk 7, Torres 6½, Mikel Merino 7½, Immobile 7, Marcos Llorente 6, Salah 6½ | | Southampton | 1 | 90 Dybala | | Half-time: | 0-0 | | Referee: | Halsey 7½ | | Attendance: | 32,380 | | Possession: | 51%-49% | | Total shots: | 13-14 | | MoM: | Gvardiol |
| | 67 Gabriel | | (4-2-1-3): Pope 7, Gusto 7, Gvardiol 8, Fabián 7, Upamecano 6½, Gabriel 6½, Díaz 6, Koopmeiners 6½ (61 Douglas Luiz 6), Dybala 7, Nkunku 7½, Kvaratskhelia 6½ | | Brighton & HA | 1 | 56 Djimsiti |
| | (4-3-3): Onana 6½, Djimsiti 6½, Olivera 7, Zielinski 7, De Ligt 6½, Rrahmani 6½, Henderson 6½, Golovin 6½, Osimhen 6, Haidara 6½, Cadamarteri 6 | | Tottenham Hotspur | 4 | 32 Mbappé, 37 Mbappé, 55 Son, 79 Kane | | Half-time: | 2-1 | | Referee: | Clattenburg 6½ | | Attendance: | 61,876 | | Possession: | 53%-47% | | Total shots: | 24-13 | | MoM: | Carvajal | | TV: | live |
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| | (1-4-2-3): Courtois 7½, Carvajal 8, Hernández 7½, Bruno Fernandes 7½, Koundé 7, Marquinhos 6½, Barella 6½, Pedri 6½, Kane 7, Son 7½, Mbappé 6½ | | Stoke City | 1 | 40 Guirassy | | 65 Guirassy, 65 Hrádecký | | (4-4-2): Hrádecký 7, Colwill 6½, Pavlovic 6½, Zaïre-Emery 7, Le Normand 6½, Van De Ven 6, Bakayoko 7½, Doué 6½, Guirassy 7 (78 Pau Cubarsí 6½), Simons 6, Isak 6½ | | West Ham United | 2 | 60 Alaba, 77 Gosens | | Half-time: | 0-0 | | Referee: | Webb 5½ | | Attendance: | 42,132 | | Possession: | 45%-55% | | Total shots: | 14-11 | | MoM: | Bernardo Silva |
| | 43 Neymar | | (4-3-3): Bijlow 6½, Klostermann 7½, Alaba 6, De Paul 7½, Can 6 (61 Kaio 6), Kimpembe 7, Estanis 7½, Gosens 6, Odubeko 5½, Isi Palazón 6½, Neymar 6½ | | Chelsea | 1 | 90+2 Rodrygo | | 8 Christensen, 18 Rodrygo | | (4-3-3): Oblak 6½, Pavard 7½, Marc Cucurella 7, Valverde 7½, Christensen 6½, Thiago Silva 6, Bernardo Silva 8, Werner 5½, Havertz 6½, Griezmann 7, Rodrygo 6 | | Wolves | 0 |
| | Half-time: | 0-0 | | Referee: | Walton 7½ | | Attendance: | 30,693 | | Possession: | 57%-43% | | Total shots: | 19-6 | | MoM: | Zambo Anguissa |
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| | (4-3-3): Strakosha 7½, Decordova-Reid 6, Castagne 7, Rúben Neves 8, Senesi 7, Luiz Felipe 7, Bergwijn 7, Raphinha 6½, Archer 5½, Keita 6, Podence 5½ | | Everton | 0 |
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| | (4-4-2): Pickford 7½, Konsa 7, Burn 7½, Zambo Anguissa 8, Branthwaite 7, Rice 7, Walker 8, Grealish 6, Watkins 5½, Álvarez 6½, Maddison 6 | | Round 22 | | Arsenal | 2 | 26 Martinelli, 45 Coman | | Half-time: | 2-0 | | Referee: | Laws 7 | | Attendance: | 59,350 | | Possession: | 53%-47% | | Total shots: | 16-10 | | MoM: | Szoboszlai |
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| | (3-5-2): Maignan 7½, Szoboszlai 8, Tah 6, Ødegaard 7, Saliba 6, Aké 7, Savinho 7, Coman 8, Matheus Cunha 7½, Fofana 6½, Martinelli 7 | | Leeds United | 0 |
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| | (3-5-2): Nübel 8, Dumfries 7½, Azpilicueta 6½, Rakitic 6½, Bastoni 6½, Nwaneri 7, Lookman 6½, Thuram 6, Saúl 6, Asensio 6½, Bentancur 6 | | Brighton & HA | 2 | 3 Golovin, 89 Golovin | | Half-time: | 1-0 | | Referee: | Pike 5½ | | Attendance: | 30,209 | | Possession: | 51%-49% | | Total shots: | 15-12 | | MoM: | Henderson |
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| | (4-3-3): Onana 7, Djimsiti 7½, Olivera 6½, Zielinski 8, De Ligt 6½, Rrahmani 6, Henderson 8, Golovin 7½, Osimhen 7½, Haidara 6½, Cadamarteri 6½ | | Nottingham Forest | 1 | 85 Gross | | 9 Gross | | (4-3-3): Henderson 6½, Tavernier 7, Davies 7, Gross 7, Koulibaly 6½, Niakhaté 6, Palmer 7, Kent 6, Scamacca 7, Awoniyi 6½, Iago 6 | | Crystal Palace | 2 | 48 Summerville, 86 Camavinga | | Half-time: | 0-1 | | Referee: | Haywood 7½ | | Attendance: | 24,993 | | Possession: | 49%-51% | | Total shots: | 15-8 | | MoM: | Camavinga |
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| | (3-5-2): Vicario 6½, Yan Couto 6½, Darmian 7½, Kim 7½, Camavinga 8, Tonali 7, Brahim 6, Nico 7½, Dani Olmo 8, Vlahovic 6½, Summerville 6 | | Wolves | 2 | 14 Castagne, 46 Archer |
| | (4-3-3): Strakosha 6½, Decordova-Reid 6½ (70 Bernardeschi 6), Castagne 7, Rúben Neves 6½, Senesi 7, Luiz Felipe 6, Podence 7, Raphinha 7½, Archer 5½, Payet 6½, Bergwijn 5½ | | Manchester City | 3 | 62 Rodri, 77 Rodri, 86 Haaland | | Half-time: | 0-2 | | Referee: | Hall 5 | | Attendance: | 54,921 | | Possession: | 62%-38% | | Total shots: | 17-13 | | MoM: | Rodri |
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| | (3-1-3-3): Ederson 6½, Bellingham 7, Gonçalo Inácio 6½, Vinícius Júnior 6, De Bruyne 7, Rodri 7½, Rúben Dias 7, Davies 6½, Foden 7, Haaland 7, Saka 6 | | Stoke City | 2 | 26 Doué, 28 Isak | | 4 Bakayoko, 29 Simons | | (4-4-2): Hrádecký 6½, Colwill 7, Pavlovic 6½, Zaïre-Emery 6½, Le Normand 6½, Van De Ven 6, Bakayoko 6½, Doué 6½, Guirassy 6½ (86 Pau Cubarsí 6), Simons 6, Isak 6½ | | Manchester United | 2 | 19 Sancho, 61 Sancho | | Half-time: | 1-3 | | Referee: | Taylor 7 | | Attendance: | 43,357 | | Possession: | 44%-56% | | Total shots: | 13-19 | | MoM: | Trippier |
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| | (4-3-3): Meret 5½, Trippier 8, Martínez 7½, Wieffer 7, Stones 7, Maguire 7, Greenwood 7, Sancho 7, Diallo 6, Jensen 6, Biancheri 6 | | Everton | 3 | 12 Grealish, 22 Grealish, 24 Álvarez |
| | (4-4-2): Pickford 6½, Konsa 7½, Burn 8, Zambo Anguissa 8, Branthwaite 7½, Rice 6½, Walker 6½, Grealish 6½, Watkins 7½, Álvarez 7, Maddison 6 | | Southampton | 1 | 86 Fabián | | Half-time: | 0-0 | | Referee: | Foster 6 | | Attendance: | 32,399 | | Possession: | 42%-58% | | Total shots: | 20-13 | | MoM: | Fabián |
| | 6 Gabriel | | (4-2-1-3): Pope 7, Gusto 7½, Gvardiol 7, Fabián 8, Upamecano 6½, Gabriel 6, Díaz 7½, Koopmeiners 6½ (66 Konaté 6), Dybala 6, Nkunku 5½, Kvaratskhelia 6 | | Colchester United | 0 |
| | 66 Buchanan, 70 Webster, 87 Willock | | (4-3-3): Trapp 7, Mazraoui 7½, Buchanan 6, Barnes 7½, Lindelöf 6½, Webster 6, Madueke 7½, Jota 6, Højlund 7, Willock 7, Nketiah 6½ | | Sunderland | 3 | 7 Cambiaso, 27 Boniface, 86 Cambiaso | | Half-time: | 2-0 | | Referee: | Hegley 5½ | | Attendance: | 52,435 | | Possession: | 55%-45% | | Total shots: | 17-15 | | MoM: | Pedro Neto |
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| | (4-4-2): Remiro 7, Cambiaso 7, Alex Grimaldo 7, Pedro Neto 8, Romagnoli 7½, Romero 7, Çalhanoglu 6½, Mac Allister 6½, Boniface 7, Dembélé 7½, Álex Baena 6½ | | Leicester City | 1 | 63 Sané |
| | (4-4-2): Raya 7, Balde 7, Dimarco 7½, Locatelli 8, Mikel 7½, Pau Torres 7, Molina 7½, Gravenberch 6, Gavi 7, Sané 6, Martínez 6½ |
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