| Round 1 (22) | Round 2 (23) |
| FC Twente - Standard | Borussia Dortmund - Sporting |
| Greuther Fürth - Club Brugge | Celtic - Greuther Fürth |
| Juventus - Manchester City | Club Brugge - Panathinaikos |
| Metz - Borussia Dortmund | L.A. Galaxy - Sporting Braga |
| Molde - Celtic | Lorient - Metz |
| Olympiakos - St.Johnstone | Manchester City - R.Madrid Castilla |
| Panathinaikos - VfL Bochum | Milan - Viktoria Plzen |
| R.Madrid Castilla - Lorient | St.Johnstone - FC Twente |
| Sporting - L.A. Galaxy | Standard - Olympiakos |
| Sporting Braga - Milan | VfL Bochum - Molde |
| Viktoria Plzen - Vålerenga | Vålerenga - Juventus |
|
| Round 3 (24) | Round 4 (25) |
| FC Twente - Club Brugge | Borussia Dortmund - Juventus |
| Greuther Fürth - Vålerenga | Celtic - Olympiakos |
| Juventus - VfL Bochum | Club Brugge - Molde |
| Metz - Manchester City | L.A. Galaxy - R.Madrid Castilla |
| Molde - St.Johnstone | Lorient - Viktoria Plzen |
| Olympiakos - Milan | Manchester City - Sporting Braga |
| Panathinaikos - L.A. Galaxy | Milan - FC Twente |
| R.Madrid Castilla - Standard | St.Johnstone - Metz |
| Sporting - Lorient | Standard - Greuther Fürth |
| Sporting Braga - Borussia Dortmund | VfL Bochum - Sporting |
| Viktoria Plzen - Celtic | Vålerenga - Panathinaikos |
|
| Round 5 (26) | Round 6 (27) |
| FC Twente - Vålerenga | Borussia Dortmund - Manchester City |
| Greuther Fürth - Milan | Club Brugge - Standard |
| Juventus - St.Johnstone | Juventus - Viktoria Plzen |
| Metz - Celtic | Lorient - L.A. Galaxy |
| Molde - Manchester City | Milan - Celtic |
| Olympiakos - VfL Bochum | Molde - FC Twente |
| Panathinaikos - Borussia Dortmund | Olympiakos - Greuther Fürth |
| R.Madrid Castilla - Club Brugge | Panathinaikos - Sporting Braga |
| Sporting - Standard | R.Madrid Castilla - St.Johnstone |
| Sporting Braga - Lorient | Sporting - Metz |
| Viktoria Plzen - L.A. Galaxy | Vålerenga - VfL Bochum |
|
| Round 7 (28) | Round 8 (29) |
| Celtic - R.Madrid Castilla | Celtic - VfL Bochum |
| FC Twente - Olympiakos | Club Brugge - L.A. Galaxy |
| Greuther Fürth - Molde | FC Twente - Sporting Braga |
| L.A. Galaxy - Borussia Dortmund | Juventus - Sporting |
| Manchester City - Lorient | Lorient - Borussia Dortmund |
| Metz - Panathinaikos | Manchester City - Greuther Fürth |
| Sporting Braga - Juventus | Milan - Vålerenga |
| St.Johnstone - Club Brugge | Olympiakos - Molde |
| Standard - Vålerenga | R.Madrid Castilla - Metz |
| VfL Bochum - Milan | Standard - St.Johnstone |
| Viktoria Plzen - Sporting | Viktoria Plzen - Panathinaikos |
|
| Round 9 (30) | Round 10 (31) |
| Borussia Dortmund - Club Brugge | Celtic - Manchester City |
| Greuther Fürth - FC Twente | Club Brugge - Lorient |
| L.A. Galaxy - Manchester City | FC Twente - Sporting |
| Metz - Olympiakos | Greuther Fürth - Juventus |
| Molde - Milan | Milan - R.Madrid Castilla |
| Panathinaikos - Juventus | Molde - Panathinaikos |
| Sporting - R.Madrid Castilla | Olympiakos - Viktoria Plzen |
| Sporting Braga - Viktoria Plzen | St.Johnstone - Sporting Braga |
| St.Johnstone - Lorient | Standard - Borussia Dortmund |
| VfL Bochum - Standard | VfL Bochum - L.A. Galaxy |
| Vålerenga - Celtic | Vålerenga - Metz |
|
| Round 11 (32) | Round 12 (33) |
| Borussia Dortmund - VfL Bochum | Borussia Dortmund - Celtic |
| Juventus - Club Brugge | Juventus - Molde |
| L.A. Galaxy - Vålerenga | L.A. Galaxy - Milan |
| Lorient - Olympiakos | Lorient - FC Twente |
| Manchester City - Standard | Manchester City - VfL Bochum |
| Metz - Milan | Metz - Club Brugge |
| Panathinaikos - Greuther Fürth | Panathinaikos - Olympiakos |
| R.Madrid Castilla - FC Twente | R.Madrid Castilla - Vålerenga |
| Sporting - Celtic | Sporting - St.Johnstone |
| Sporting Braga - Molde | Sporting Braga - Greuther Fürth |
| Viktoria Plzen - St.Johnstone | Viktoria Plzen - Standard |
|
| Round 13 (34) | Round 14 (35) |
| Celtic - L.A. Galaxy | Borussia Dortmund - St.Johnstone |
| Club Brugge - Viktoria Plzen | Juventus - Standard |
| FC Twente - Juventus | L.A. Galaxy - FC Twente |
| Greuther Fürth - R.Madrid Castilla | Lorient - VfL Bochum |
| Milan - Borussia Dortmund | Manchester City - Milan |
| Molde - Sporting | Metz - Molde |
| Olympiakos - Sporting Braga | Panathinaikos - Celtic |
| St.Johnstone - Manchester City | R.Madrid Castilla - Olympiakos |
| Standard - Panathinaikos | Sporting - Vålerenga |
| VfL Bochum - Metz | Sporting Braga - Club Brugge |
| Vålerenga - Lorient | Viktoria Plzen - Greuther Fürth |
|
| Round 15 (36) | Round 16 (37) |
| Celtic - Lorient | Borussia Dortmund - Olympiakos |
| Club Brugge - Manchester City | Juventus - Celtic |
| FC Twente - Panathinaikos | L.A. Galaxy - Greuther Fürth |
| Greuther Fürth - Metz | Lorient - Milan |
| Milan - Sporting | Manchester City - Vålerenga |
| Molde - Viktoria Plzen | Metz - Standard |
| Olympiakos - Juventus | Panathinaikos - St.Johnstone |
| St.Johnstone - L.A. Galaxy | R.Madrid Castilla - Molde |
| Standard - Sporting Braga | Sporting - Club Brugge |
| VfL Bochum - R.Madrid Castilla | Sporting Braga - VfL Bochum |
| Vålerenga - Borussia Dortmund | Viktoria Plzen - FC Twente |
|
| Round 17 (38) | Round 18 (39) |
| FC Twente - Celtic | Club Brugge - Vålerenga |
| Greuther Fürth - St.Johnstone | FC Twente - Metz |
| Juventus - Milan | Greuther Fürth - VfL Bochum |
| Metz - L.A. Galaxy | Juventus - L.A. Galaxy |
| Molde - Standard | Molde - Borussia Dortmund |
| Olympiakos - Club Brugge | Olympiakos - Sporting |
| Panathinaikos - Lorient | Panathinaikos - R.Madrid Castilla |
| R.Madrid Castilla - Borussia Dortmund | Sporting Braga - Celtic |
| Sporting - Manchester City | St.Johnstone - Milan |
| Sporting Braga - Vålerenga | Standard - Lorient |
| Viktoria Plzen - VfL Bochum | Viktoria Plzen - Manchester City |
|
| Round 19 (40) | Round 20 (41) |
| Borussia Dortmund - Viktoria Plzen | Club Brugge - VfL Bochum |
| Celtic - Club Brugge | FC Twente - Manchester City |
| L.A. Galaxy - Standard | Greuther Fürth - Borussia Dortmund |
| Lorient - Molde | Juventus - Lorient |
| Manchester City - Olympiakos | Molde - Vålerenga |
| Metz - Sporting Braga | Olympiakos - L.A. Galaxy |
| Milan - Panathinaikos | Panathinaikos - Sporting |
| R.Madrid Castilla - Juventus | Sporting Braga - R.Madrid Castilla |
| Sporting - Greuther Fürth | St.Johnstone - Celtic |
| VfL Bochum - FC Twente | Standard - Milan |
| Vålerenga - St.Johnstone | Viktoria Plzen - Metz |
|
| Round 21 (42) |
| Borussia Dortmund - FC Twente |
| Celtic - Standard |
| L.A. Galaxy - Molde |
| Lorient - Greuther Fürth |
| Manchester City - Panathinaikos |
| Metz - Juventus |
| Milan - Club Brugge |
| R.Madrid Castilla - Viktoria Plzen |
| Sporting - Sporting Braga |
| VfL Bochum - St.Johnstone |
| Vålerenga - Olympiakos |
League rounds 22-42 (in brackets) are the respective return ties of rounds 1-21 above,
ie. round 42 is Club Brugge - Milan, FC Twente - Borussia Dortmund etc. |