Crowd | | | Opponents |
| | | | | | | | | | | | | | | | | | | | | | | | 47,204 | A | 2 (1) | Fiorentina | L | 1-3 | 0-2 |
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 81 | 9 | 10 | 11b | 5 |
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| | 41,968 | H | 2 (2) | Chelsea | W | 3-1 | 1-0 | - -
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 82 | 9 | 101 | 11 | 5 | 7 |
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| | 46,453 | H | 2 (4) | Sevilla | W | 3-1 | 1-1 | 0
| 1 | 2 | 31 | 4 | 5 | 6 | 7 | 8 | 91 | 101 | 11 | 5 | 7 |
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| | 45,803 | H | IS 1 | Arsenal¹ | L | 3-4 | 2-1 |
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 92 | 10 | 111 | 5 | 7 |
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| | 43,735 | H | WCT 1 {1} | Real Sociedad | W | 3-2 | 2-1 |
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 82 | 9 | 10 | 111 | 5 | 7 |
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| | 47,726 | A | 2 (5) | West Ham United | W | 4-1 | 1-1 | 6
| 1 | 2 | 3 | 4 | 5 | 6 | 71 | 8 | 9 | 101 | 111 | 5 | 71 |
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| | 31,874 | A | WCT 1 | Real Sociedad¹ | L | 1-3 | 1-2 |
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 91 | 10b | 11 | 5 |
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| | 50,380 | H | 2 (6) | Real Betis | W | 3-1 | 2-1 | 3
| 1 | 21 | 3 | 41 | 5 | 6 | 7 | 8 | 9b | 10 | 111b | 5 | 7 |
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| | 51,981 | A | 2 (7) | Spartak | L | 1-4 | 1-3 | 3
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 101 | 11 | 5 |
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| | 54,985 | A | 2 (3) | Valencia | X | 2-2 | 1-2 | - -
| 1 | 21 | 3 | 4 | 5 | 6 | 7 | 8 | 91 | 10 | 11 |
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| | 50,270 | H | 2 (8) | Manchester United | X | 2-2 | 1-2 | 4
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| 3 | 4 | 6 |
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| 8 | 91 | 7 |
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| 1 | 2 | 5 | 10 | 11 | 8 | | 45,650 | A | 2 (9) | Napoli | L | 1-2 | 1-1 | 5
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| 3 | 4 | 6 |
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| 8 | 91 | 7 |
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| 1 | 2 | 5 | 10 | 11 | 8 | | 48,175 | H | 2 (10) | Fenerbahçe | L | 1-3 | 0-2 | 6
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| 3 | 4 | 6 |
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| 8 | 9 | 7 |
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| 1 | 2 | 5 | 10 | 11 |
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| A | 2 (11) | Milan |
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| A | 2 (12) | Strasbourg |
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| H | 2 (13) | Sporting |
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| A | 2 (14) | Inter |
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| H | 2 (15) | VfB Stuttgart |
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| A | 2 (16) | Tottenham Hotspur |
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| A | 2 (17) | Villarreal |
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| H | 2 (18) | Arsenal |
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| A | 2 (19) | Atalanta |
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| H | 2 (20) | B.Mönchengladbach |
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| A | 2 (21) | FC Twente |
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| H | 2 (22) | Fiorentina |
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| A | 2 (23) | Chelsea |
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| H | 2 (24) | Valencia |
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| A | 2 (25) | Sevilla |
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| H | 2 (26) | West Ham United |
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| A | 2 (27) | Real Betis |
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| H | 2 (28) | Spartak |
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| A | 2 (29) | Manchester United |
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| H | 2 (30) | Napoli |
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| A | 2 (31) | Fenerbahçe |
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| H | 2 (32) | Milan |
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| H | 2 (33) | Strasbourg |
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| A | 2 (34) | Sporting |
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| H | 2 (35) | Inter |
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| A | 2 (36) | VfB Stuttgart |
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| H | 2 (37) | Tottenham Hotspur |
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| H | 2 (38) | Villarreal |
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| A | 2 (39) | Arsenal |
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| H | 2 (40) | Atalanta |
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| A | 2 (41) | B.Mönchengladbach |
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| H | 2 (42) | FC Twente |
| | Key: 2 - Division 2, {#} - leg number, (#) - league round number and ¹ - after extra-time. |
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