Crowd | | | Opponents |
| | | | | | | | | | | | | | | | | 42,841 | A | 2 (1) | RB Leipzig | W | 1-0 | 0-0 |
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 91 | 10 | 11 | 2 | | 48,414 | H | 2 (2) | Atalanta | O | 0-0 | 0-0 | - -
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 |
| | 44,522 | A | 2 (3) | Sporting | L | 1-2 | 1-1 | - -
| 1 | 2 | 31 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 |
| | 29,197 | H | IS 1 | Imotski | W | 5-0 | 4-0 |
| 1 | 21 | 3 | 41 | 5 | 6 | 71 | 81 | 91 | 10 | 11 |
| | 28,163 | A | WCT 1 {1} | Real Betis | O | 0-0 | 0-0 |
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 |
| | 18,070 | A | 2 (5) | Lille | L | 2-3 | 1-3 | 15
| 1 | 2 | 31 | 4 | 5 | 6 | 7 | 81 | 9 | 10 | 11 |
| | 32,326 | H | WCT 1 | Real Betis³ | X | 2-2 | 1-2 |
| 1 | 2 | 3 | 4 | 5 | 61 | 7 | 81 | 9 | 10 | 11 |
| | 37,380 | A | 2 (6) | Valencia | L | 0-1 | 0-0 | 17
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 |
| | 41,456 | H | 2 (7) | Manchester City | X | 2-2 | 1-1 | 21
| 1 | 2 | 31 | 4 | 5 | 6 | 7 | 8 | 91 | 10 | 11 |
| | 45,155 | H | 2 (4) | Torino | X | 1-1 | 1-1 | 20
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 81 | 9 | 10 | 11 |
| | 29,835 | A | IS 2 | Vitória Guimarães | W | 2-1 | 1-0 |
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 81 | 9 | 101 | 11 |
| | 45,329 | A | 2 (8) | Fiorentina | L | 1-3 | 1-2 | 17
| 1 | 2 | 3 | 4 | 5 | 6 | 71 | 8 | 9 | 10 | 11 |
| | 40,222 | H | 2 (9) | FC Porto | W | 1-0 | 0-0 | 21
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 81 | 9 | 10 | 11 |
| | 32,066 | A | 2 (10) | Dundee United | L | 0-1 | 0-0 | 18
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10b | 11 |
| | 28,952 | A | IS 3 | Corinthians³ | X | 1-1 | 0-0 |
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 81 | 9 | 10 | 11 |
|
| H | 2 (11) | Sevilla |
|
| H | 2 (12) | Villarreal |
|
| A | 2 (13) | B.Mönchengladbach |
|
| H | 2 (14) | FC Twente |
|
| A | 2 (15) | Spartak |
|
| H | 2 (16) | Arsenal |
|
| A | 2 (17) | Aston Villa |
|
| A | 2 (18) | Sassuolo |
|
| H | 2 (19) | Tottenham Hotspur |
|
| A | 2 (20) | Napoli |
|
| H | 2 (21) | Chelsea |
|
| H | 2 (22) | RB Leipzig |
|
| A | 2 (23) | Atalanta |
|
| H | 2 (24) | Sporting |
|
| A | 2 (25) | Torino |
|
| H | 2 (26) | Lille |
|
| H | 2 (27) | Valencia |
|
| A | 2 (28) | Manchester City |
|
| H | 2 (29) | Fiorentina |
|
| A | 2 (30) | FC Porto |
|
| H | 2 (31) | Dundee United |
|
| A | 2 (32) | Sevilla |
|
| A | 2 (33) | Villarreal |
|
| H | 2 (34) | B.Mönchengladbach |
|
| A | 2 (35) | FC Twente |
|
| H | 2 (36) | Spartak |
|
| A | 2 (37) | Arsenal |
|
| H | 2 (38) | Aston Villa |
|
| H | 2 (39) | Sassuolo |
|
| A | 2 (40) | Tottenham Hotspur |
|
| H | 2 (41) | Napoli |
|
| A | 2 (42) | Chelsea |
| | Key: 2 - Division 2, {#} - leg number, (#) - league round number and ³ - away goals rule. |
|