Crowd | | | Opponents |
| | | | | | | | | | | | | | | | | 45,870 | A | 1 (1) | Manchester City | L | 1-2 | 1-1 |
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 91 | 10 | 11 |
| | 41,907 | H | 1 (2) | Bayer Leverkusen | O | 0-0 | 0-0 | - -
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
| 11 | 10 | | 34,377 | H | 1 (4) | Independiente | W | 2-0 | 1-0 | 17
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 92 | 10 | 11 | 10 | | 13,458 | A | IS 1 | Cantolagua | W | 3-0 | 1-0 |
| 1 | 2 | 3 | 41 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 102 | | 28,028 | H | WCT 1 {1} | Farroupilha | W | 3-0 | 3-0 |
| 1 | 21 | 3 | 4 | 5 | 6 | 7 | 81 | 9 | 10 | 11 | 10 | | 44,862 | A | 1 (5) | Feyenoord | L | 0-1 | 0-1 | 11
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 3 | 11 | 10 | | 12,056 | A | WCT 1 | Farroupilha | W | 2-0 | 1-0 |
| 1 | 2 | 3 | 41 | 5 | 6 | 7 | 8 | 9 | 10 | 111 | 10 | | 36,861 | H | 1 (6) | RB Leipzig | W | 2-1 | 0-1 | 16
| 1 | 2 | 3 | 4 | 51 | 6 | 7 | 8 | 9 | 10 | 111 | 10b | | 83,719 | A | 1 (7) | Lyon | L | 0-2 | 0-2 | 11
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 3 | 11 | 10 | | 47,601 | A | IS 2 | Sporting Braga | L | 1-2 | 1-1 |
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 91 | 3 | 11 | 10 |
| H | 1 (8) | Bayern München |
|
| A | 1 (9) | Newcastle United |
|
| H | 1 (10) | Ajax |
|
| A | 1 (11) | Marseille |
|
| A | 1 (12) | Real Madrid |
|
| H | 1 (13) | Sporting Braga |
|
| A | 1 (14) | Borussia Dortmund |
|
| H | 1 (15) | Barcelona |
|
| A | 1 (16) | FC Schalke 04 |
|
| A | 1 (17) | Aston Villa |
|
| A | 1 (18) | FC Porto |
|
| H | 1 (19) | Boca Juniors |
|
| A | 1 (20) | Liverpool |
|
| H | 1 (21) | Paris SG |
|
| H | 1 (22) | Manchester City |
|
| A | 1 (23) | Bayer Leverkusen |
|
| H | 1 (24) | Deportivo |
|
| A | 1 (25) | Independiente |
|
| H | 1 (26) | Feyenoord |
|
| A | 1 (27) | RB Leipzig |
|
| H | 1 (28) | Lyon |
|
| A | 1 (29) | Bayern München |
|
| H | 1 (30) | Newcastle United |
|
| A | 1 (31) | Ajax |
|
| H | 1 (32) | Marseille |
|
| H | 1 (33) | Real Madrid |
|
| A | 1 (34) | Sporting Braga |
|
| H | 1 (35) | Borussia Dortmund |
|
| A | 1 (36) | Barcelona |
|
| H | 1 (37) | FC Schalke 04 |
|
| H | 1 (38) | Aston Villa |
|
| H | 1 (39) | FC Porto |
|
| A | 1 (40) | Boca Juniors |
|
| H | 1 (41) | Liverpool |
|
| A | 1 (42) | Paris SG |
| | Key: 1 - Division 1, {#} - leg number and (#) - league round number. |
|