| Round 5 | | Deportivo | 0 |
| | Half-time: | 0-0 | | Referee: | Uilenberg 7½ | | Attendance: | 59,540 | | Possession: | 43%-57% | | Total shots: | 12-15 | | MoM: | Jorginho |
| | 9 Bonucci, 45 Bonucci | | (4-3-3): Szczesny 6, Baku 7, Digne 6½, Jorginho 8, Bonucci 6, Stanisic 6, Kesler-Hayden 6½, Mikel 7 (53 Rakitic 6½), Zirkzee 7, Bentancur 6½, Torres 6½ | | RB Leipzig | 2 | 47 Raum, 90+1p Sørloth |
| | (4-3-3): Blaswich 6, Adarabioyo 6½, Raum 7½, Kampl 7, Martínez 8, Halstenberg 7, Álvaro Djaló 7, Ritchie 7, Sørloth 8, Nketiah 5½, Joelinton 6½ | | FC Augsburg | 2 | 40 Okafor, 53 Tapsoba | | Half-time: | 1-0 | | Referee: | Ziober 6 | | Attendance: | 32,182 | | Possession: | 44%-56% | | Total shots: | 10-9 | | MoM: | Lotomba |
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| | (4-3-3): Pigliacelli 7, Lotomba 8, Tsimikas 6, Grillitsch 7½, Tapsoba 6 (84 Framberger 6), Pongracic 6½, Vignato 7, González 6½, Calvert-Lewin 6½, Vargas 6, Okafor 6 | | Milan | 0 |
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| | (4-3-3): Nübel 7½, Teze 7½, Darmian 7, Kökçü 7, Dier 7, Koulibaly 6½, Tsyhankov 7½, Philippe Coutinho 7, Gómez 6, Nianzou 6, Kean 6½ | | FC Basel | 2 | 23 Van Wolfswinkel, 26p Van Wolfswinkel | | Half-time: | 2-1 | | Referee: | Jorge Corroado 6 | | Attendance: | 30,313 | | Possession: | 44%-56% | | Total shots: | 11-17 | | MoM: | Damsgaard | | TV: | highlights |
| | 70 Seferovic, 84 Kouyaté | | (4-3-3): Omlin 6½, Xhaka 7½, Rodriguez 7½, Alan 7½, Cömert 7½, Kouyaté 6½, Frei 6½, Millar 6, Van Wolfswinkel 6, Ramires 7½, Seferovic 6 | | Inter | 1 | 16 João Moutinho | | 4 João Moutinho | | (4-3-3): Fabianski 6½, Veltman 7, Young 7, Soucek 7, Vestergaard 7, Pessina 6, Pépé 7, Damsgaard 7½, Iheanacho 7, João Moutinho 7 (68 Doucouré 6), Pinamonti 6 | | FC Twente | 2 | 66p Wilson, 81 Stengs | | Half-time: | 0-0 | | Referee: | Krondl 6½ | | Attendance: | 13,168 | | Possession: | 50%-50% | | Total shots: | 13-7 | | MoM: | Lokonga | | TV: | live |
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| | (4-3-3): Pavlenka 7, Mingueza 7, Blind 6½, Lokonga 7½, Vlaar 6½, St Juste 6½, Stengs 7½, Saelemaekers 7, Wilson 7, Cavani 6, Berghuis 6 | | Spartak | 1 | 48 Lee | | 7 Chukwueze, 74 Nico | | (4-3-3): Aréola 7, Reynolds 7½, Manu Sánchez 6½, Pasalic 6½, Djimsiti 6½ (60 Amavi 7), Bailly 6, Haraldsson 6, Chukwueze 7, Zapata 6½, Nico 6½, Lee 6½ | | Fenerbahçe | 1 | 38 Dursun | | Half-time: | 1-2 | | Referee: | Craciun 7 | | Attendance: | 50,434 | | Possession: | 51%-49% | | Total shots: | 15-15 | | MoM: | Alioski |
| | 43 Muriqi, 88 Alioski | | (4-3-3): Samba 6, Kadioglu 7, Alioski 7, Irfan Can 7, Reyes 6½, Neustädter 6, Mert Hakan 6, Valbuena 7, Muriqi 7, Jailson 6½, Dursun 6½ (82 Yüksek 6) | | Paris SG | 2 | 25 Trossard, 40p De Ketelaere | | 79 Mancini | | (4-3-3): Lloris 6½, Semedo 7, Marc Cucurella 7, Cristante 7, Mancini 7, Yoro 6, Almiron 7, Otavio 7 (51 Sancet 7), De Ketelaere 6½, Trossard 7, Gnonto 6½ | | Manchester United | 1 | 64 Barcola | | Half-time: | 0-0 | | Referee: | Levnikov 8 | | Attendance: | 54,599 | | Possession: | 51%-49% | | Total shots: | 8-10 | | MoM: | Xhaka | | TV: | highlights |
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| | (4-3-3): Mendy 7, Walker 7, Alex Telles 6½, Koke 7½, Dendoncker 6, Diomandé 5, Florenzi 6½, Barcola 7½, Insigne 6½, Freuler 7, Dybala 6 | | Arsenal | 1 | 47 Mkhitaryan | | 37 Balogun | | (4-3-3): Turner 7½, Azpilicueta 7, Marcos Alonso 7, Xhaka 7½, Pablo 5½, Chambers 6½, Fábio Vieira 6½ (48 Cozier-Duberry 6), Mkhitaryan 7½, Mayoral 7, Kramer 6½, Balogun 5½ | | Real Betis | 4 | 34 Doan, 63 Feddal, 67 Feddal, 77 Doan | | Half-time: | 1-1 | | Referee: | Reijgwart 6 | | Attendance: | 42,587 | | Possession: | 41%-59% | | Total shots: | 11-17 | | MoM: | Maffeo |
| | 52 Ayoze, 85 Brais Méndez | | (4-3-3): Sergio 6, Ruibal 7½, Feddal 7½, Rodríguez 7½, Álvaro 6½, Lascelles 6½, Brais Méndez 6, Doan 7½, Loren 7, Ayoze 5½, Tello 5½ | | VfB Stuttgart | 2 | 21 Kim, 50 Führich |
| | (4-3-3): Nicolas 6½, Maffeo 8, Ito 7½, Endo 7½, Kim 7½, Kempf 7 (64 Insúa 6½), Mangala 7, Führich 7½, Guirassy 7½, Karazor 6, Arnautovic 6 | | Roma | 1 | 77 Pedro | | Half-time: | 0-0 | | Referee: | Young 6½ | | Attendance: | 26,345 | | Possession: | 47%-53% | | Total shots: | 11-10 | | MoM: | Okaka | | TV: | highlights |
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| | (4-3-3): Svilar 7½, Zeki 7½, Marchizza 6½ (69 Missori 6½), Tahirovic 7, Smalling 7½, Fornasier 6½, Orsolini 7, Pedro 7, Okaka 8, Portu 5½, Shomuradov 7 | | Aberdeen | 0 |
| | 13 Gómez, 39 Lovren | | (4-3-3): Tatarusanu 7½, Johnston 7½, N'Soki 7, Maitland-Niles 7½, Dunk 6½, Lovren 7, Kennedy 7, Gómez 6½, Benedetto 6½, Poveda 5½, Ramirez 6½ | | Sevilla | 1 | 10 Banega | | Half-time: | 1-2 | | Referee: | Brito Arceo 7 | | Attendance: | 41,890 | | Possession: | 47%-53% | | Total shots: | 16-13 | | MoM: | Musiala |
| | 84 Álex Moreno | | (4-3-3): Dmitrovic 6, Álex Pozo 6½ (77 Óscar 6), Fran García 7, Gudelj 6½, Sergio Ramos 7, Gnagnon 6½, Banega 6, Álex Moreno 6½, En-Nesyri 6½, Fernando 6½, El Haddadi 6 | | Newcastle United | 2 | 20 Rashford, 42 Gray | | 24 Bruno Fernandes | | (4-3-3): Ramsdale 6½, Gray 6, Shaw 6, Aké 7½, White 7, Willock 6½, Palmer 7½, Gordon 7, Rashford 6½, Bruno Fernandes 7, Musiala 7½ | | Sporting | 3 | 11 Rafa, 62 Toni, 79 Coates | |
| | (4-3-3): Rui Silva 7, Dani Alves 6½, Silva 6½, Anderson Talisca 7½, Coates 7½, Mattheus 6, Pizzi 7½, Rafa 7½, Beto 6½, Marega 6, Toni 6 | | Valencia | 0 |
| | 1 Racic, 53 Kondogbia | | (4-3-3): Soria 7, Thierry Correia 7½, Samuel Lino 7½, Parejo 7, Gabriel Paulista 7, Cenk 6, Kondogbia 7, Hélder Costa 7, Rubén Sobrino 7, Racic 6, Rodrigo 6 | | Tottenham Hotspur | 4 | 12 Daka, 36 Sarr, 44 Daka, 49 Colwill | | Half-time: | 3-3 | | Referee: | Detruche 6½ | | Attendance: | 33,458 | | Possession: | 57%-43% | | Total shots: | 13-8 | | MoM: | Adli |
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| | (4-3-3): Karius 6, Pedro Porro 5 (54 Mendy 6½), Colwill 7½, Sarr 7½, Coady 7½, Schulz 6½, Tolisso 7, Golovin 7½, Daka 7, Lo Celso 8, Sargent 6 | | Rangers | 3 | 10 Gelson Martins, 24 Gelson Martins, 30 Gelson Martins | | 20 Kalajdzic | | (4-3-3): Strakosha 6, Lucas 6½, Bellerín 7, Adli 8, Goldson 6½ (50 Lawrence 6½), Keïta 5½, Strootman 6, Gelson Martins 7, Kalajdzic 6½, Colak 6, Rebic 6 | | Round 4 | | Arsenal | 4 | 6 Mkhitaryan, 26 Xhaka, 33 Azpilicueta, 37 Fábio Vieira | | Half-time: | 4-0 | | Referee: | Onufer 6½ | | Attendance: | 38,374 | | Possession: | 55%-45% | | Total shots: | 17-6 | | MoM: | Azpilicueta |
| | 81 Balogun | | (4-3-3): Turner 7½, Azpilicueta 8, Marcos Alonso 7, Xhaka 7, Pablo 7, Chambers 6, Fábio Vieira 5 (48 Cozier-Duberry 7½), Mkhitaryan 7, Mayoral 6½, Kramer 7, Balogun 6½ | | Real Betis | 0 |
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| | (4-3-3): Sergio 7, Ruibal 7, Feddal 6, Rodríguez 7½, Álvaro 7, Lascelles 6, Brais Méndez 7, Doan 7, Loren 6½ (69 Dilrosun 7), Ayoze 6, Tello 6 | | Round 3 | | Sporting | 1 | 27 Rafa | | Half-time: | 1-1 | | Referee: | Walton 5½ | | Attendance: | 45,424 | | Possession: | 45%-55% | | Total shots: | 12-16 | | MoM: | Manu Sánchez |
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| | (4-3-3): Rui Silva 6, Dani Alves 7, Silva 7, Anderson Talisca 7½, Coates 7, Mattheus 6, Pizzi 6½, Rafa 7, Beto 5½, Marega 6, Toni 7 | | Spartak | 2 | 21 Chukwueze, 73 Zapata |
| | (4-3-3): Aréola 7, Reynolds 6½, Manu Sánchez 7½, Pasalic 6½, Djimsiti 6½ (73 Amavi 6), Bailly 6, Haraldsson 7, Chukwueze 7½, Zapata 7, Nico 7, Lee 6½ |
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