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| Round 1 (22) AEK - FC Basel Aberdeen - Athletic Bilbao Everton - Grêmio FC Augsburg - Leeds United Fenerbahçe - Parma Nice - Lazio Rangers - Zenit Real Betis - Vitória Guimarães Real Sociedad - Celtic Udinese - Anderlecht West Ham United - Roma | Round 2 (23) Anderlecht - Rangers Athletic Bilbao - Udinese Celtic - Nice FC Basel - Everton Grêmio - AEK Lazio - Aberdeen Leeds United - Real Sociedad Parma - Real Betis Roma - Fenerbahçe Vitória Guimarães - West Ham United Zenit - FC Augsburg |
| Round 3 (24) AEK - Lazio Aberdeen - Parma Everton - Vitória Guimarães FC Augsburg - Anderlecht Fenerbahçe - FC Basel Nice - Leeds United Rangers - Grêmio Real Betis - Athletic Bilbao Real Sociedad - Zenit Udinese - Roma West Ham United - Celtic | Round 4 (25) Anderlecht - Nice Athletic Bilbao - West Ham United Celtic - Rangers FC Basel - FC Augsburg Grêmio - Real Betis Lazio - Everton Leeds United - Udinese Parma - AEK Roma - Real Sociedad Vitória Guimarães - Fenerbahçe Zenit - Aberdeen |
| Round 5 (26) AEK - Roma Aberdeen - Celtic Everton - Athletic Bilbao FC Augsburg - Parma Fenerbahçe - Anderlecht Nice - Zenit Rangers - Vitória Guimarães Real Betis - Lazio Real Sociedad - Grêmio Udinese - FC Basel West Ham United - Leeds United | Round 6 (27) AEK - Real Betis Athletic Bilbao - Roma Fenerbahçe - Everton Lazio - Parma Leeds United - Anderlecht Rangers - FC Basel Real Sociedad - FC Augsburg Udinese - Aberdeen Vitória Guimarães - Grêmio West Ham United - Nice Zenit - Celtic |
| Round 7 (28) Aberdeen - Real Sociedad Anderlecht - Zenit Celtic - Leeds United Everton - AEK FC Augsburg - West Ham United FC Basel - Vitória Guimarães Grêmio - Athletic Bilbao Nice - Udinese Parma - Rangers Real Betis - Fenerbahçe Roma - Lazio | Round 8 (29) AEK - Fenerbahçe Aberdeen - West Ham United Anderlecht - Real Betis Everton - Nice Grêmio - FC Basel Lazio - Athletic Bilbao Parma - Roma Rangers - FC Augsburg Udinese - Real Sociedad Vitória Guimarães - Celtic Zenit - Leeds United |
| Round 9 (30) Athletic Bilbao - Parma Celtic - Anderlecht FC Augsburg - AEK FC Basel - Zenit Fenerbahçe - Lazio Leeds United - Vitória Guimarães Nice - Aberdeen Real Betis - Everton Real Sociedad - Rangers Roma - Grêmio West Ham United - Udinese | Round 10 (31) AEK - Aberdeen Athletic Bilbao - FC Augsburg Everton - Real Sociedad FC Basel - Nice Fenerbahçe - West Ham United Grêmio - Leeds United Lazio - Rangers Parma - Anderlecht Real Betis - Udinese Roma - Celtic Vitória Guimarães - Zenit |
| Round 11 (32) Aberdeen - FC Basel Anderlecht - Grêmio Celtic - Athletic Bilbao FC Augsburg - Lazio Leeds United - Roma Nice - Fenerbahçe Rangers - Everton Real Sociedad - Parma Udinese - Vitória Guimarães West Ham United - Real Betis Zenit - AEK | Round 12 (33) Aberdeen - Grêmio Anderlecht - Roma Celtic - Lazio FC Augsburg - Vitória Guimarães Leeds United - Parma Nice - Real Betis Rangers - Athletic Bilbao Real Sociedad - FC Basel Udinese - Fenerbahçe West Ham United - AEK Zenit - Everton |
| Round 13 (34) AEK - Nice Athletic Bilbao - Zenit Everton - Udinese FC Basel - Anderlecht Fenerbahçe - Real Sociedad Grêmio - West Ham United Lazio - Leeds United Parma - Celtic Real Betis - Rangers Roma - FC Augsburg Vitória Guimarães - Aberdeen | Round 14 (35) Aberdeen - Real Betis Anderlecht - Lazio Celtic - Everton FC Augsburg - Fenerbahçe Leeds United - FC Basel Nice - Vitória Guimarães Rangers - AEK Real Sociedad - Athletic Bilbao Udinese - Grêmio West Ham United - Parma Zenit - Roma |
| Round 15 (36) AEK - Udinese Athletic Bilbao - Leeds United Everton - West Ham United FC Basel - Celtic Fenerbahçe - Aberdeen Grêmio - Nice Lazio - Real Sociedad Parma - Zenit Real Betis - FC Augsburg Roma - Rangers Vitória Guimarães - Anderlecht | Round 16 (37) Aberdeen - Everton Anderlecht - Athletic Bilbao Celtic - Real Betis FC Augsburg - Grêmio Leeds United - AEK Nice - Roma Rangers - Fenerbahçe Real Sociedad - Vitória Guimarães Udinese - Parma West Ham United - FC Basel Zenit - Lazio |
| Round 17 (38) AEK - Vitória Guimarães Aberdeen - Roma Everton - Parma FC Augsburg - Celtic Fenerbahçe - Grêmio Nice - Athletic Bilbao Rangers - Leeds United Real Betis - FC Basel Real Sociedad - Anderlecht Udinese - Lazio West Ham United - Zenit | Round 18 (39) AEK - Real Sociedad Aberdeen - Anderlecht Everton - FC Augsburg FC Basel - Lazio Fenerbahçe - Leeds United Grêmio - Zenit Nice - Parma Real Betis - Roma Udinese - Celtic Vitória Guimarães - Athletic Bilbao West Ham United - Rangers |
| Round 19 (40) Anderlecht - AEK Athletic Bilbao - FC Basel Celtic - Grêmio FC Augsburg - Nice Lazio - West Ham United Leeds United - Aberdeen Parma - Vitória Guimarães Rangers - Udinese Real Sociedad - Real Betis Roma - Everton Zenit - Fenerbahçe | Round 20 (41) AEK - Celtic Aberdeen - FC Augsburg Everton - Anderlecht FC Basel - Parma Fenerbahçe - Athletic Bilbao Grêmio - Lazio Nice - Rangers Real Betis - Leeds United Udinese - Zenit Vitória Guimarães - Roma West Ham United - Real Sociedad |
| Round 21 (42) Anderlecht - West Ham United Athletic Bilbao - AEK Celtic - Fenerbahçe FC Augsburg - Udinese Lazio - Vitória Guimarães Leeds United - Everton Parma - Grêmio Rangers - Aberdeen Real Sociedad - Nice Roma - FC Basel Zenit - Real Betis | |
| League rounds 22-42 (in brackets) are the respective return ties of rounds 1-21 above, i.e. round 42 is AEK - Athletic Bilbao, Aberdeen - Rangers etc. | |