| Round 3 | | Hansa Rostock | 1 | 38 Biereth | | Half-time: | 1-0 | | Referee: | D'Urso 7½ | | Attendance: | 28,805 | | Possession: | 42%-58% | | Total shots: | 12-18 | | MoM: | Nkounkou | | TV: | live |
| | 75 Ryerson | | (4-3-3): Unnerstall 7, Ryerson 6½, Nkounkou 8, Kampl 6½ (46 Brooks 7½), Stark 7, Sagnan 6½, Aránguiz 7, Arnautovic 7, Biereth 7, Fran Pérez 5½, Suárez 5½ | | Leeds United | 1 | 81 Wöber |
| | (4-3-3): Jörgensen 7½, Kristensen 7, Struijk 7, Rutter 7½, Koch 6½ (71 Bamford 6), Wöber 7, Yunus 7, Harrison 7½, Antonio 7½, Aaronson 7, Summerville 7 | | Lyon | 1 | 61 Ristic | | Half-time: | 0-1 | | Referee: | Ilie 9½ | | Attendance: | 41,330 | | Possession: | 52%-48% | | Total shots: | 11-10 | | MoM: | Caqueret |
| | 68 Toko Ekambi | | (4-3-3): Turati 7, Dubois 7, Chilwell 6½, Caqueret 7½, Danilo 7½, Chambers 6½, Özcan 6½, Ristic 6½, Diallo 7½, Vanaken 7, Toko Ekambi 6 | | Zaragoza | 1 | 43 Williams | | 28 Williams | | (4-3-3): Atubolu 7, Fran Gámez 6½, Espino 7, Millot 6½, Aidoo 6½, Ahmetcan 6½, Larrazabal 7, Williams 6½, Milik 7 (62 Brown 6½), Luis Alberto 6, Beier 6½ | | Rayo Vallecano | 0 |
| | Half-time: | 0-0 | | Referee: | Wieser 6½ | | Attendance: | 14,554 | | Possession: | 44%-56% | | Total shots: | 11-14 | | MoM: | Dante |
| | 8 Bebé, 53 Isi Palazón, 54 Mumin, 60 Lejeune | | (4-3-3): Dimitrievski 6, Iván 6½, Lejeune 6½, Isi Palazón 7½, Catena 7½, Mumin 6, Andrés 6, Santi Comesańa 7, Falcao 6½, Ciss 7, Bebé 5½ | | Nice | 2 | 71 Thomasson, 81 Dante |
| | (4-3-3): Dupé 6½, Clauss 7½, Nandjou 7½, Rosario 7, Dante 8, Ndayishimiye 7, Ndombélé 7, Thomasson 7, Orakpo 5½, Diop 6½ (68 Boudaoui 6), Laborde 6 | | Round 4 | | 1.FC Union Berlin | 3 | 11 Jeong, 20 Haberer, 49p Hollerbach | | Half-time: | 2-1 | | Referee: | Bettin 5½ | | Attendance: | 21,812 | | Possession: | 44%-56% | | Total shots: | 10-10 | | MoM: | Catena |
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| | (4-3-3): Rřnnow 6½, Trimmel 6½, Roussillon 6½, Khedira 7½, Doekhi 6½, Querfeld 6, Skarke 6½, Jeong 5½ (54 Bénes 6½), Hollerbach 6½, Haberer 6½, Ljubicic 5½ | | Rayo Vallecano | 2 | 21 Falcao, 89 Santi Comesańa | | 70 Ciss | | (4-3-3): Dimitrievski 6, Iván 7½, Lejeune 8, Isi Palazón 7, Catena 8, Mumin 7, Andrés 6, Santi Comesańa 8, Falcao 7, Ciss 7, Bebé 6 | | AIK | 1 | 61 Ajeti | | Half-time: | 0-0 | | Referee: | Jemmott 7 | | Attendance: | 34,943 | | Possession: | 48%-52% | | Total shots: | 10-11 | | MoM: | Turati |
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| | (4-3-3): Plogmann 7, Holm 7, Benito 7½, Hussein 6½, Starfelt 7½, Helander 6½, Frei 6, Zuber 6½, Larsson 6½ (69 Ofori 7), Ajeti 6, Sarr 6 | | Lyon | 0 |
| | 13 Toko Ekambi, 45+2 Caqueret | | (4-3-3): Turati 8, Dubois 6½, Chilwell 7, Caqueret 7, Danilo 7, Chambers 6½, Özcan 6½, Ristic 7, Diallo 6½, Vanaken 7½, Toko Ekambi 6 | | FC Schalke 04 | 0 |
| | Half-time: | 0-0 | | Referee: | Golanski 9½ | | Attendance: | 39,083 | | Possession: | 57%-43% | | Total shots: | 10-16 | | MoM: | Kenny |
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| | (4-3-3): Vandevoordt 7, Kenny 8, Friedl 6½, Mollet 7 (71 Belahyane 8), Nastasic 7½, Belocian 6, Aydin 7½, Chaďbi 6½, Boujellab 6, Schöpf 6, Matondo 6½ | | Ferencváros | 0 |
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| | (4-3-3): Dibusz 8, Marcos Rocha 6½, Ramírez 6½, Keďta 7½, Milic 6½, Raul Gustavo 6, Abu Fani 6, Zachariassen 6½, Ishak 6, Ben Romdhane 6½, Luciano 7 | | Feyenoord | 0 |
| | Half-time: | 0-1 | | Referee: | Afful 9 | | Attendance: | 40,169 | | Possession: | 57%-43% | | Total shots: | 11-17 | | MoM: | Wieffer |
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| | (4-3-3): Kelly 7, Nieuwkoop 7½, Malacia 7½, Wieffer 8, Tapia 6, Martins-Indi 6, McCausland 7 (85 Pedersen 6), Igor Paixâo 7, Miovski 7, Jahanbakhsh 6½, Vente 6½ | | Sevilla | 1 | 42 El Haddadi | | 3 Kike Salas, 70 En-Nesyri, 85 Lamela, 90 En-Nesyri | | (4-3-3): Remiro 6½, Mercado 7, Marc Cucurella 7½, Amadou 6½, Kike Salas 6½, Carmona 6, Banega 6½, Gil 7 (85 Vázquez 6), En-Nesyri 6½, Lamela 6½, El Haddadi 6½ | | Fort. Düsseldorf | 3 | 24 Klaus, 59 Pléa, 64 Amiri | | Half-time: | 1-1 | | Referee: | Racalbuto 7½ | | Attendance: | 33,897 | | Possession: | 55%-45% | | Total shots: | 18-13 | | MoM: | Laimer |
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| | (4-3-3): Ortega 7, Laimer 8, Gavory 6½, André 7½, Hilgers 7, Dragovic 6½, Pléa 5½ (60 Hoffmann 6), Klaus 5½, Demirbay 7, Amiri 7½, Appelkamp 6½ | | Manchester United | 1 | 17 Mejbri | | 19 Antony | | (3-5-2): Dieng 6, Wan-Bissaka 6, Mejbri 6, Kingdon 6½, McNair 7, Fry 6, Crooks 6½, McAllister 5½, Latte Lath 6½, Wheatley 6½, Antony 6½ | | Gręmio | 2 | 10 Zé Rafael, 49 Wooh | | Half-time: | 1-0 | | Referee: | Trentalange 5½ | | Attendance: | 43,669 | | Possession: | 51%-49% | | Total shots: | 16-9 | | MoM: | Cabrera |
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| | (4-3-3): Éverson 7, Fagner 7½, Fábio 6½, Villasanti 7½, Wooh 7, Rodrigo Caio 6, Carballo 6½, Zé Rafael 6 (64 Wallace 7½), Pratto 7, Bitello 6½, Ferreira 5½ | | Mallorca | 0 |
| | 19 Kadewere, 23 Brasanac, 59 Iago | | (4-3-3): Iago 7, Corchia 7½, Cabrera 8½, Ruiz De Galarreta 7½, Raillo 7, Valjent 6½, Brasanac 7, Tello 6½ (58 Cufré 7), Prats 6½, Álex 6, Kadewere 6½ | | Leeds United | 4 | 6 Antonio, 9 Harrison, 20 Antonio, 65 Harrison | | Half-time: | 3-0 | | Referee: | Benkö 5½ | | Attendance: | 36,326 | | Possession: | 56%-44% | | Total shots: | 16-7 | | MoM: | Aaronson |
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| | (4-3-3): Jörgensen 7½, Kristensen 6½, Struijk 6½, Rutter 7, Koch 6½, Wöber 7, Yunus 6½, Harrison 7½, Antonio 7½, Aaronson 7½, Summerville 7 | | Real Betis | 0 |
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| | (4-3-3): Toni Fuidias 6½, Arias 7 (69 Canales 7), Bruno Peres 6½, Fabián 7, Bartra 7, Vítor Hugo 6, Luiz Henrique 6½, Lainez 5½, Loren 7, William Carvalho 7, Beltrán 6 | | Nice | 1 | 15 Thomasson | | Half-time: | 1-0 | | Referee: | Piraux 7½ | | Attendance: | 36,038 | | Possession: | 44%-56% | | Total shots: | 10-18 | | MoM: | Ehizibue | | TV: | highlights |
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| | (4-3-3): Dupé 6, Clauss 6½, Nandjou 6½, Rosario 7, Dante 5½, Ndayishimiye 6½, Ndombélé 6½, Thomasson 6½, Orakpo 6, Guessand 6, Laborde 7 | | Udinese | 2 | 67p Beto, 88 Ehizibue |
| | (4-3-3): Provedel 6½, Isla 7 (67 Sturaro 6), Masina 7½, Fofana 7, Battaglia 7½, Opoku 7, Ehizibue 8, Barák 6½, Beto 7, Pereyra 6½, Muriel 6½ | | Parma | 2 | 1p Bonny, 20 Bonny | | Half-time: | 2-0 | | Referee: | Nielsen 5½ | | Attendance: | 27,843 | | Possession: | 53%-47% | | Total shots: | 13-16 | | MoM: | Bonny |
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| | (4-3-3): Dragowski 7, O'Brien 7, Darmian 7½, Bonaventura 7, Circati 7, Solet 6, Bernabé 7½, Vlasic 7½, Bonny 7½, Zé Eduardo 6 (50 Augello 6), Paloschi 5½ | | Hansa Rostock | 1 | 70 Biereth |
| | (4-3-3): Unnerstall 7, Ryerson 6½, Nkounkou 7, Kampl 6½ (65 Suárez 6), Stark 6½, Kempf 6, Aránguiz 7 (85 De Sart 6), Arnautovic 6½, Biereth 7, Fran Pérez 6, Eggestein 6 | | Vélez Sársfield | 2 | 3 Orellano, 90+1 Calleri | | Half-time: | 1-1 | | Referee: | Korac 5½ | | Attendance: | 37,715 | | Possession: | 52%-48% | | Total shots: | 9-15 | | MoM: | Álvaro Fernández |
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| | (4-3-3): Rulli 7, Saravia 7½, Ortega 6, Ramírez 8, Gómez 6, De Los Santos 6½, Cristaldo 7, Orellano 7, Calleri 7, Di Santo 6, Bou 6½ | | CSKA | 1 | 33 Zhemaletdinov |
| | (4-3-3): Müller 7, Gajic 7½, Álvaro Fernández 8½, Oblyakov 7 (90+2 Chernikov 6), Vasin 6, Makeev 6½, Kryskiv 6½, Ejuke 7, Necid 6, Sucic 6½, Zhemaletdinov 6 | | Zaragoza | 3 | 32 Williams, 51 Milik, 63 Milik | | Half-time: | 1-1 | | Referee: | Řvrebř 6½ | | Attendance: | 44,580 | | Possession: | 48%-52% | | Total shots: | 17-10 | | MoM: | Espino |
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| | (4-3-3): Atubolu 7, Fran Gámez 6, Espino 8, Millot 5½ (75 Brown 7½), Aidoo 6½, Ahmetcan 6, Larrazabal 7, Williams 7, Milik 7, Luis Alberto 6, Beier 5½ | | Club Brugge | 1 | 23 Onyedika | | 1 Vetlesen | | (4-3-3): Wellenreuther 6½, Faes 7, Mćhle 6, Onyedika 7, Buongiorno 7, Mancini 7, Ferguson 6½, Vetlesen 7, Zirkzee 7, Nielsen 7 (68 Odoi 6), Thiago 6 |
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