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| Round 1 (22) AEK - Barcelona Ajax - Arsenal FC Basel - Marseille Genoa - Napoli Juventus - Osasuna Lazio - Deportivo Lens - Liverpool Newcastle United - Flamengo Paris SG - Inter Sassuolo - Anderlecht Shakhtar - Celtic | Round 2 (23) Anderlecht - AEK Arsenal - Sassuolo Barcelona - Newcastle United Celtic - Genoa Deportivo - Juventus Flamengo - Lazio Inter - FC Basel Liverpool - Shakhtar Marseille - Paris SG Napoli - Lens Osasuna - Ajax |
| Round 3 (24) AEK - Liverpool Ajax - Deportivo FC Basel - Anderlecht Genoa - Arsenal Juventus - Flamengo Lazio - Inter Lens - Marseille Newcastle United - Napoli Paris SG - Celtic Sassuolo - Osasuna Shakhtar - Barcelona | Round 4 (25) Anderlecht - Paris SG Arsenal - Lazio Barcelona - Genoa Celtic - Lens Deportivo - AEK Flamengo - Sassuolo Inter - Shakhtar Liverpool - FC Basel Marseille - Juventus Napoli - Ajax Osasuna - Newcastle United |
| Round 5 (26) AEK - Arsenal Ajax - Inter FC Basel - Napoli Genoa - Osasuna Juventus - Liverpool Lazio - Celtic Lens - Flamengo Newcastle United - Marseille Paris SG - Barcelona Sassuolo - Deportivo Shakhtar - Anderlecht | Round 6 (27) Ajax - Juventus Anderlecht - Liverpool Barcelona - Napoli Celtic - Inter Deportivo - Arsenal FC Basel - Shakhtar Genoa - Sassuolo Lazio - Marseille Lens - Paris SG Newcastle United - AEK Osasuna - Flamengo |
| Round 7 (28) AEK - Ajax Arsenal - Osasuna Flamengo - Deportivo Inter - Barcelona Juventus - Genoa Liverpool - Lazio Marseille - Celtic Napoli - Anderlecht Paris SG - FC Basel Sassuolo - Newcastle United Shakhtar - Lens | Round 8 (29) AEK - Genoa Anderlecht - Barcelona Celtic - Arsenal Deportivo - Osasuna FC Basel - Lens Flamengo - Shakhtar Inter - Marseille Lazio - Juventus Liverpool - Napoli Newcastle United - Ajax Paris SG - Sassuolo |
| Round 9 (30) Ajax - Lazio Arsenal - Flamengo Barcelona - Liverpool Genoa - Newcastle United Juventus - FC Basel Lens - Anderlecht Marseille - Deportivo Napoli - Inter Osasuna - Celtic Sassuolo - AEK Shakhtar - Paris SG | Round 10 (31) Anderlecht - Lazio Barcelona - Juventus Celtic - Deportivo FC Basel - AEK Inter - Osasuna Lens - Genoa Liverpool - Flamengo Marseille - Sassuolo Napoli - Arsenal Paris SG - Ajax Shakhtar - Newcastle United |
| Round 11 (32) AEK - Marseille Ajax - Liverpool Arsenal - Barcelona Deportivo - FC Basel Flamengo - Inter Genoa - Shakhtar Juventus - Anderlecht Lazio - Paris SG Newcastle United - Celtic Osasuna - Napoli Sassuolo - Lens | Round 12 (33) AEK - Inter Ajax - Marseille Arsenal - Anderlecht Deportivo - Paris SG Flamengo - Napoli Genoa - FC Basel Juventus - Celtic Lazio - Barcelona Newcastle United - Lens Osasuna - Liverpool Sassuolo - Shakhtar |
| Round 13 (34) Anderlecht - Osasuna Barcelona - Deportivo Celtic - AEK FC Basel - Sassuolo Inter - Genoa Lens - Ajax Liverpool - Arsenal Marseille - Flamengo Napoli - Juventus Paris SG - Newcastle United Shakhtar - Lazio | Round 14 (35) AEK - Shakhtar Ajax - Barcelona Arsenal - Paris SG Deportivo - Napoli Flamengo - Anderlecht Genoa - Liverpool Juventus - Lens Lazio - FC Basel Newcastle United - Inter Osasuna - Marseille Sassuolo - Celtic |
| Round 15 (36) Anderlecht - Ajax Barcelona - Osasuna Celtic - Flamengo FC Basel - Newcastle United Inter - Sassuolo Lens - AEK Liverpool - Deportivo Marseille - Arsenal Napoli - Lazio Paris SG - Genoa Shakhtar - Juventus | Round 16 (37) AEK - Paris SG Ajax - Celtic Arsenal - Shakhtar Deportivo - Anderlecht Flamengo - Barcelona Genoa - Marseille Juventus - Inter Lazio - Lens Newcastle United - Liverpool Osasuna - FC Basel Sassuolo - Napoli |
| Round 17 (38) AEK - Napoli Ajax - Flamengo FC Basel - Celtic Genoa - Deportivo Juventus - Arsenal Lazio - Osasuna Lens - Inter Newcastle United - Anderlecht Paris SG - Liverpool Sassuolo - Barcelona Shakhtar - Marseille | Round 18 (39) AEK - Flamengo Celtic - Barcelona FC Basel - Ajax Genoa - Lazio Inter - Deportivo Lens - Osasuna Marseille - Anderlecht Newcastle United - Arsenal Paris SG - Juventus Sassuolo - Liverpool Shakhtar - Napoli |
| Round 19 (40) Ajax - Shakhtar Anderlecht - Genoa Arsenal - Inter Barcelona - Marseille Deportivo - Lens Flamengo - FC Basel Juventus - Sassuolo Lazio - Newcastle United Liverpool - Celtic Napoli - Paris SG Osasuna - AEK | Round 20 (41) AEK - Juventus Celtic - Napoli FC Basel - Arsenal Genoa - Ajax Inter - Anderlecht Lens - Barcelona Marseille - Liverpool Newcastle United - Deportivo Paris SG - Flamengo Sassuolo - Lazio Shakhtar - Osasuna |
| Round 21 (42) Ajax - Sassuolo Anderlecht - Celtic Arsenal - Lens Barcelona - FC Basel Deportivo - Shakhtar Flamengo - Genoa Juventus - Newcastle United Lazio - AEK Liverpool - Inter Napoli - Marseille Osasuna - Paris SG | |
| League rounds 22-42 (in brackets) are the respective return ties of rounds 1-21 above, i.e. round 42 is AEK - Lazio, Celtic - Anderlecht etc. | |