| | League position: | 9 | | Home league form: | WWWL | | Overall league form: | WWWWWWWL | | Formation: | 3-4-1-2 |
| | | Line-ups | | EDERSON Santana | 6½ | 1 | 6½ | Emiliano MARTÍNEZ | | Daniel CARVAJAL | 6½ | 2 | 7 | Reece JAMES | | Milan SKRINIAR | 8 | 3 | 6½ | Mykola MATVIYENKO | | (c,p,f)Cristiano RONALDO | 7 | 4 | 7 | Declan RICE(c) | | RÚBEN Santos DIAS | 6½ | 5 | 7 | Giovanni DI LORENZO | | Timo WERNER | 6 | 6 | 6½ | Illya ZABARNYI | | Kevin DE BRUYNE | 7 | 7 | 7 | Harvey ELLIOTT | | Virgil VAN DIJK | 7½ | 8 | 7 | Jordan HENDERSON | | Thomas MÜLLER | 6½ | 9 | 6½ | Jesús FERREIRA(p) | | Nicola ZALEWSKI | 7 | 10 | 6½ | Phil FODEN(f) | | RODRI | 7½ | 11 | 6 | Jonathan DAVID | | Lee Avramovic | Manager | Dan Tatam | | Ibrahima KONATÉ | | 12 | | Harry WINKS | | Samir HANDANOVIC | | 13 | | Jan OBLAK | | Douglas AREZO | | 14 | 6 | Viktor TSYHANKOV | | Nicolò ROVELLA | | 15 | 6 | Aleksandr GOLOVIN | | Victor BONIFACE | | 16 | | Nahuel MOLINA |
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| | | | League position: | 13 | | Away league form: | WLOX | | Overall league form: | WLXOXLXW | | Formation: | 4-4-2 |
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