| Round 21 | | Barnsley | 1 | 45+2 David | | Half-time: | 1-1 | | Referee: | Reed 6½ | | Attendance: | 48,649 | | Possession: | 55%-45% | | Total shots: | 15-12 | | MoM: | Rice |
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| | (3-5-2): Oblak 7, Quansah 7½, Hincapié 7, Rice 8½, McGinn 7½, Maguire 6½, Di Lorenzo 7, Elliott 6½, David 7, Foden 6½, Golovin 6½ | | Norwich City | 2 | 10 Mbappé, 88 Mbappé | | 17 Mbappé | | (4-4-2): Donnarumma 6½, Milenkovic 7, Balde 7½, Gatti 7, Wirtz 7½, Diomandé 6, Mkhitaryan 7, Camavinga 6, Endrick 6, Fermín 7½, Mbappé 6½ | | Bury | 0 |
| | Half-time: | 0-1 | | Referee: | Styles 5½ | | Attendance: | 54,261 | | Possession: | 45%-55% | | Total shots: | 9-12 | | MoM: | Hernández | | TV: | highlights |
| | 87 Bremer | | (4-4-2): Martínez 7, Wan-Bissaka 7½, Robertson 8, Çalhanoglu 7, Orban 6½, Djimsiti 7, Spinazzola 6½, Williams 7, Embolo 7½, Barella 7, Gnabry 7 (76 Bremer 6) | | Wrexham | 1 | 27 Gakpo |
| | (4-3-3): Diogo Costa 7½, Stiller 6, Hernández 8, Pau Cubarsí 7, Bastoni 7½, Gravenberch 6½, Gakpo 7½, Locatelli 6½, Kane 7, Havertz 6½ (81 Ricci 6), Davies 7 | | Cambridge United | 1 | 61 Álvarez | | Half-time: | 0-0 | | Referee: | Knight 6½ | | Attendance: | 80,437 | | Possession: | 54%-46% | | Total shots: | 17-11 | | MoM: | Partey | | TV: | live |
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| | (3-4-3): Raya 6½, Elvedi 6½, Marc Cucurella 7½, Partey 7½, Koch 7, Laimer 6½, Marusic 6, Yéremy Pino 7, Watkins 7, Álvarez 6, Rafael Leăo 7½ | | Manchester United | 1 | 74 Politano | | 22 Brandt | | (4-3-3): Gulácsi 6½, Akanji 7, Mendy 7 (62 Lucas Paquetá 6½), Pellegrini 7, Rüdiger 6, Diego Carlos 6½, Salah 7, Politano 6½, Sřrloth 6½, Brandt 5½, Taremi 5½ | | Coventry City | 1 | 34 Demirovic | | Half-time: | 1-0 | | Referee: | D'Urso 7 | | Attendance: | 52,142 | | Possession: | 49%-51% | | Total shots: | 14-11 | | MoM: | Boscagli |
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| | (4-3-3): Milinkovic-Savic 7½, Castagne 6½, Boscagli 8½, De Roon 7, Aguerd 7, Dimarco 6½, Demirovic 7, Til 6, Gyökeres 7, Mikel Merino 7, Trossard 6 | | Crystal Palace | 0 |
| | 44 Sánchez | | (4-3-2-1): Sánchez 7, James 7, Bard 6, Koke 8, Thiaw 7½, Colwill 6½, Palmer 7, Kökçü 7 (81 Durán 6), Burkardt 6½, Tonali 6, Samardzic 5½ | | FC Halifax Town | 2 | 45+1 Isak, 79 Isak | | Half-time: | 1-0 | | Referee: | Beeby 8 | | Attendance: | 45,442 | | Possession: | 50%-50% | | Total shots: | 16-15 | | MoM: | Raum |
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| | (4-3-3): Hrádecký 8, Ryerson 7, Mćhle 6½, Christensen 8, Hien 7, Hjulmand 7, Kulusevski 6, Larsson 6 (81 Andersen 6), Hřjlund 7, Damsgaard 6½, Isak 7 | | QPR | 0 |
| | 71 Beier | | (4-3-3): Vicario 7½, Matheus Nunes 6, Raum 8, Sarr 7 (66 Solanke 6), Danso 6½ (57 Stroeykens 6½), Miguel 7½, Mac Allister 7, Brais Méndez 6½, Mikel 6½, Beier 6, Ndoye 6 | | Liverpool | 2 | 52 Coman, 57 Vinícius Júnior | | Half-time: | 0-0 | | Referee: | Penicka 6 | | Attendance: | 62,598 | | Possession: | 41%-59% | | Total shots: | 17-19 | | MoM: | Coman |
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| | (3-4-3): Neuer 7½, Upamecano 7½, Mancini 7, Marcos Llorente 6½, Marquinhos 7, Fabián 6½, Greenwood 7½, Rodrygo 6½, Osimhen 7, Vinícius Júnior 7, Coman 8 | | Swindon Town | 1 | 61 Savinho | | 54 Summerville | | (4-4-2): Kelleher 7, Livramento 7½, De Cuyper 7, Doyle 7½, Collins 7, Zabarnyi 6½, Summerville 6, Savinho 6½, Zirkzee 6½, Gilmour 6½, Johnson 6 | | Port Vale | 0 |
| | Half-time: | 0-1 | | Referee: | Clattenburg 7½ | | Attendance: | 38,499 | | Possession: | 36%-64% | | Total shots: | 9-11 | | MoM: | Bradley | | TV: | highlights |
| | 20 Blind | | (3-5-2): Pau López 7, Vitík 5½, Agoumé 7, Sucic 7, Otávio 6½, Blind 7, Reyna 6, Dinkçi 6, Ekitiké 7 (61 Ordońez 7½), Diarra 6½, Sterling 6 | | Portsmouth | 1 | 37 Martínez | | 55 Kimmich | | (4-4-2): Szczesny 7, Digne 7, Kimmich 6½, Gündogan 6½, Bradley 8½, Kehrer 6½, Zubimendi 7, Saka 7½, Martínez 6½, Cristante 6, Lukaku 6½ | | Swansea City | 0 |
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| | (3-4-3): Alisson 5½, Rrahmani 6, Alaba 6½, Gabriel 7, Díaz 6½, Szoboszlai 7, Bernardo Silva 7½, Lookman 7½, Dembélé 6½, Dybala 6½, Thuram 6½ | | Tottenham Hotspur | 2 | 60 Kvaratskhelia, 86 Bellingham |
| | (3-5-2): Pickford 6, White 7, Robinson 7½, Zambo Anguissa 7, Stones 7, Bellingham 6, Alexander-Arnold 8, Eze 6½, Bowen 6, Kvaratskhelia 6, Rashford 6½ | | Wolves | 2 | 82 Yamal, 87 Vlahovic | | Half-time: | 0-2 | | Referee: | Marriner 6 | | Attendance: | 41,813 | | Possession: | 51%-49% | | Total shots: | 17-12 | | MoM: | Lewis | | TV: | highlights |
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| | (5-2-3): Sommer 6½, Lewis 7½, Nuno Mendes 7½, Tah 7½, Schlotterbeck 6½, Kovacic 7, Yamal 7½, Éderson 6, Vlahovic 7½, Douglas Luiz 6½, Nico Williams 6½ | | Macclesfield FC | 3 | 25 Griezmann, 45 Son, 59 Di María |
| | (4-1-3-2): Maignan 6, Bah 7½, Alex Grimaldo 7, Rabiot 7½, Romero 6½, Süle 6, Di María 7, Barcola 6, Son 7, Sancet 6½, Griezmann 6 | | York City | 1 | 21 Lacazette | | Half-time: | 1-1 | | Referee: | Atkinson 6½ | | Attendance: | 29,406 | | Possession: | 48%-52% | | Total shots: | 14-15 | | MoM: | Sabitzer |
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| | (4-3-3): Bounou 6, Marcos Alonso 6½, Sabitzer 8, Masuaku 7, Kolasinac 7½, Danilo 7½, Olise 7½, Kostic 7½, Lacazette 6½, Wissa 6½, Tadic 6½ | | Hull City | 1 | 19 Galeno |
| | (4-2-3-1): Courtois 8, Mazraoui 7, Kerkez 7, Bentancur 7½, Martínez 7, Timber 7½, Doku 7, Guendouzi 7 (71 Pavlovic 7), Gonçalo Ramos 6½, Kluivert 7 (71 Schjelderup 6), Galeno 6 | | Round 22 | | Crystal Palace | 1 | 9 Thiaw | | Half-time: | 1-1 | | Referee: | Bates 6 | | Attendance: | 59,329 | | Possession: | 51%-49% | | Total shots: | 19-17 | | MoM: | Robertson |
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| | (4-3-2-1): Sánchez 6½, James 7, Bard 7½, Koke 8, Thiaw 8, Colwill 7½, Palmer 7½, Kökçü 6½ (81 Durán 6), Burkardt 6, Caicedo 7, Samardzic 6 | | Bury | 1 | 20 Embolo |
| | (4-4-2): Martínez 6½, Wan-Bissaka 7½, Robertson 8, Çalhanoglu 7, Aké 6½, Djimsiti 7, Spinazzola 7½, Williams 8, Embolo 8, Barella 6½, Gnabry 6½ | | Hull City | 2 | 28 Gonçalo Ramos, 82 Mazraoui | | Half-time: | 1-1 | | Referee: | Jones 6½ | | Attendance: | 61,098 | | Possession: | 52%-48% | | Total shots: | 19-10 | | MoM: | Kerkez |
| | 41 Timber | | (4-2-3-1): Courtois 7, Mazraoui 7½, Kerkez 8½, Bentancur 7, Martínez 7½, Timber 6, Doku 8, Guendouzi 6½ (66 Pavlovic 6½), Gonçalo Ramos 6½, Kluivert 6 (66 Rodrigo Ribeiro 6), Galeno 6½ | | FC Halifax Town | 2 | 42p Hřjlund, 62 Hřjlund |
| | (4-3-3): Hrádecký 6, Ryerson 7, Mćhle 7½, Christensen 7, Hien 6½, Hjulmand 6½, Kulusevski 6½, Larsson 7 (81 Andersen 6), Hřjlund 6½, Damsgaard 6½, Isak 6½ | | Macclesfield FC | 0 |
| | Half-time: | 0-1 | | Referee: | Williamson 6 | | Attendance: | 46,091 | | Possession: | 50%-50% | | Total shots: | 14-15 | | MoM: | Di Lorenzo |
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| | (4-1-3-2): Maignan 7, Bah 6½, Alex Grimaldo 6½, Rabiot 7½, Romero 6½, Süle 6½, Di María 7, Barcola 7, Son 6½, Sancet 6½, Griezmann 6 | | Barnsley | 1 | 20 Foden |
| | (3-5-2): Oblak 7½, Quansah 7, Hincapié 7½, Rice 6½, McGinn 7, Maguire 7, Di Lorenzo 8, Elliott 6½, David 5½, Foden 6, Golovin 7 | | Manchester United | 4 | 5 Politano, 19p Sřrloth, 36og Blind, 90+1 Sřrloth | | Half-time: | 3-1 | | Referee: | Russell 5 | | Attendance: | 41,551 | | Possession: | 57%-43% | | Total shots: | 14-9 | | MoM: | Brandt |
| | 12 Brandt | | (4-3-3): Gulácsi 6, Akanji 7, Mendy 7½, Pellegrini 7½, Rüdiger 7, Diego Carlos 6½, Salah 8, Politano 6½, Sřrloth 7, Brandt 8, Taremi 6½ | | Port Vale | 2 | 16 Otávio, 58p Ekitiké | | 21 Sterling | | (3-5-2): Pau López 6½, Vitík 6½, Agoumé 5½, Sucic 7, Otávio 6½, Blind 6½, Reyna 6½, Dinkçi 6½, Ekitiké 7 (61 Ordońez 7), Diarra 6½, Sterling 6 | | Norwich City | 0 |
| | Half-time: | 0-0 | | Referee: | Webster 6½ | | Attendance: | 81,672 | | Possession: | 50%-50% | | Total shots: | 16-9 | | MoM: | Bounou |
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| | (4-4-2): Donnarumma 7½, Milenkovic 6½, Balde 6½, Gatti 7, Wirtz 8, Diomandé 7, Mkhitaryan 6, Camavinga 6½, Endrick 6, Fermín 6, Mbappé 7½ | | York City | 0 |
| | 72 Wissa | | (4-3-3): Bounou 8, Marcos Alonso 6, Sabitzer 7½, Masuaku 8, Kolasinac 7½, Danilo 7, Olise 7, Kostic 7, Lacazette 6½, Wissa 6½, Tadic 6 | | QPR | 1 | 18 Ndoye | | Half-time: | 1-0 | | Referee: | Hegley 6½ | | Attendance: | 40,373 | | Possession: | 55%-45% | | Total shots: | 18-10 | | MoM: | Miguel |
| | 20 Matheus Nunes | | (4-3-3): Vicario 8, Matheus Nunes 6, Raum 7½, Sarr 7, Danso 6½, Miguel 8, Mac Allister 7, Brais Méndez 7, Mikel 6½, Beier 6½ (76 Paredes 6), Ndoye 7 (80 Schär 6) | | Swindon Town | 0 |
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| | (4-4-2): Kelleher 7½, Livramento 6, De Cuyper 7½, Doyle 7½, Collins 7, Zabarnyi 7, Summerville 6, Savinho 6½, Zirkzee 6½, Gilmour 7, Johnson 6 | | Tottenham Hotspur | 2 | 52p Bowen, 68 Bowen | | Half-time: | 0-0 | | Referee: | Penton 7½ | | Attendance: | 88,598 | | Possession: | 52%-48% | | Total shots: | 15-13 | | MoM: | Zambo Anguissa |
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| | (3-5-2): Pickford 6, White 8, Robinson 6 (83 Mbeumo 6), Zambo Anguissa 8, Stones 7½, Bellingham 8, Alexander-Arnold 7, Eze 6, Bowen 7½, Kvaratskhelia 7½, Rashford 7 | | Coventry City | 2 | 47 Demirovic, 82 Gyökeres | | 2 Trossard | | (4-3-3): Milinkovic-Savic 6, Castagne 6, Boscagli 6½, De Roon 7, Aguerd 6, Dimarco 6½, Demirovic 7, Til 5½, Gyökeres 6½, Mikel Merino 6, Trossard 6½ | | Wolves | 2 | 45+1p Vlahovic, 81 Nico Williams | | Half-time: | 1-2 | | Referee: | Thorpe 5 | | Attendance: | 51,319 | | Possession: | 41%-59% | | Total shots: | 11-16 | | MoM: | Nuno Mendes |
| | 73 Vlahovic | | (5-2-3): Sommer 6½, Lewis 6½, Nuno Mendes 8, Tah 7½, Schlotterbeck 7, Kovacic 6½, Yamal 6, Éderson 7, Vlahovic 7, Douglas Luiz 6, Nico Williams 5½ | | Cambridge United | 2 | 5 Álvarez, 24 Watkins |
| | (3-4-3): Raya 6, Elvedi 6½, Marc Cucurella 6½, Partey 6½, Koch 7½, Laimer 6, Marusic 7½, Yéremy Pino 6½, Watkins 6½, Álvarez 7½, Rafael Leăo 7 | | Wrexham | 2 | 21 Kane, 60 Kane | | Half-time: | 1-2 | | Referee: | Friend 6½ | | Attendance: | 79,611 | | Possession: | 50%-50% | | Total shots: | 12-17 | | MoM: | Greenwood |
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| | (4-3-3): Diogo Costa 7, Stiller 6, Hernández 6½, Pau Cubarsí 7, Bastoni 6, Gravenberch 6 (77 Doué 6), Gakpo 6½ (77 Sancho 6), Locatelli 6½, Kane 7, Havertz 6½, Davies 5½ | | Liverpool | 3 | 3p Osimhen, 17 Vinícius Júnior, 76 Vinícius Júnior |
| | (3-4-3): Neuer 6, Upamecano 6½, Mancini 7½, Marcos Llorente 7, Marquinhos 6, Fabián 7, Greenwood 7½, Rodrygo 7, Osimhen 7, Vinícius Júnior 7, Coman 7½ |
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