| Round 21 | | Barnsley | 3 | 12 Beltrán, 52 Foden, 87og Xhaka | | Half-time: | 1-0 | | Referee: | Dowd 6 | | Attendance: | 42,424 | | Possession: | 52%-48% | | Total shots: | 19-18 | | MoM: | Oblak | | TV: | highlights |
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| | (4-4-2): Oblak 7½, Molina 6½, Maguire 7, Rice 7, Longstaff 6½, Matviyenko 6½, Elliott 7½, McGinn 7, Beltrán 6½, Foden 7, Grealish 7 | | Crewe Alexandra | 0 |
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| | (4-3-3): Leno 7½, De Vrij 7, Xhaka 7, Richarlison 6½, Hakimi 7, Guerreiro 7, Morata 7, William Carvalho 6½, Milinkovic-Savic 6, Dani Olmo 6½, Rafa 6 | | Bristol Rovers | 1 | 58og João Cancelo | | Half-time: | 0-1 | | Referee: | Foy 7½ | | Attendance: | 47,937 | | Possession: | 44%-56% | | Total shots: | 6-18 | | MoM: | Alaba |
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| | (4-3-3): Rui Patrício 7, Frankowski 6½, Tagliafico 6½, Rabiot 7, Guehi 6½, Koulibaly 6½, Danso 6, Pedro Neto 6½, Vargas 5½, Chukwueze 6, González 6 | | Swansea City | 1 | 15 Bernardo Silva |
| | (3-4-3): Alisson 7, Hernández 7, Alaba 8, Gabriel 7, João Cancelo 7½, Szoboszlai 7, Frimpong 7½, Bernardo Silva 7, Dybala 7½, Mané 7, Benzema 7 | | Liverpool | 4 | 3 Brahim, 11 Vinícius Júnior, 20 Vinícius Júnior, 74 Osimhen | | Half-time: | 3-0 | | Referee: | D'Urso 6½ | | Attendance: | 69,960 | | Possession: | 55%-45% | | Total shots: | 11-11 | | MoM: | Zielinski |
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| | (3-4-3): Neuer 7, Araújo 6, Upamecano 7, Marcos Llorente 7, Marquinhos 6, Zielinski 8, Brahim 7, Osimhen 6½, Lewandowski 7½, Vinícius Júnior 7, Coman 7½ | | Bury | 1 | 47 Immobile | | 60 Gnabry, 72 Orban | | (4-4-2): Schmeichel 7½, Spinazzola 7, Robertson 7½, Orban 7, Aké 7, Bremer 6½, Çalhanoglu 7, Shaw 6½, Immobile 7, Jota 5½, Gnabry 6½ | | Manchester United | 0 |
| | Half-time: | 0-0 | | Referee: | Beeby 7 | | Attendance: | 70,272 | | Possession: | 56%-44% | | Total shots: | 14-6 | | MoM: | Akanji |
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| | (4-3-3): Gulácsi 7½, Akanji 9, Mendy 8, Lucas Paquetá 7 (49 Alderweireld 8), Rüdiger 7, Martínez Quarta 6, Salah 8, Brandt 6½, Pepê 6½, Pellegrini 7, Rodrygo 7½ | | Crystal Palace | 0 |
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| | (4-3-3): Courtois 7, Cuadrado 6½, Alex Sandro 7, Zubimendi 7, Varane 6½, Bonucci 6, Zaniolo 7, Palhinha 5½, Joselu 7, Koke 6½, Mbappé 6½ | | Norwich City | 1 | 34 Núñez | | Half-time: | 1-0 | | Referee: | Walton 7 | | Attendance: | 37,990 | | Possession: | 60%-40% | | Total shots: | 12-7 | | MoM: | Camavinga | | TV: | highlights |
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| | (4-4-2): Donnarumma 7, Milenkovic 7, Balde 7½, António Silva 7½, Diaby 7, García 7½, Camavinga 8, Wirtz 7½, Vitor Roque 7, Kvaratskhelia 7, Núñez 7 | | Wolves | 0 |
| | 31 Verratti, 72 Kovacic | | (4-3-3): Nübel 7½, Calabria 6½, Nuno Mendes 6, Vlahovic 6½, Nico Williams 7½, Tah 6, Tapsoba 6, Verratti 5½, Gabriel Jesus 6, Kovacic 6½, Can 6½ | | Portsmouth | 0 |
| | Half-time: | 0-1 | | Referee: | Clattenburg 6½ | | Attendance: | 54,133 | | Possession: | 51%-49% | | Total shots: | 10-18 | | MoM: | Hernández | | TV: | highlights |
| | 21 Kimmich | | (4-4-2): Szczesny 6½, Digne 6½, Gündogan 5½, Brozovic 7, Laporte 7, Giménez 6½, Saka 7½, Cristante 6, Raphinha 6, Kimmich 6½, Lukaku 6½ | | Wrexham | 1 | 12 Kane |
| | (4-3-3): Ter Stegen 7, Ginter 7, Hernández 8, Saliba 6½, Bastoni 6½, Locatelli 7, Chiesa 7, Kroos 6½, Kane 7, Goretzka 6½, Davies 6½ | | QPR | 1 | 66 Elmas | |
| | (4-3-3): Vicario 6, João Mário 6½ (57 Zhegrova 6), Raum 7½, Mac Allister 7, Le Normand 7, Schär 6½, Paredes 6½ (57 Beier 7), Elmas 6½, Vlasic 7, Solanke 7, Adli 6 | | Port Vale | 2 | 37 Mitoma, 78 Horta | | 51 Mitoma | | (4-2-1-3): Sommer 7½, Rodon 7½, Emerson Palmieri 8, Bonaventura 7½, Blind 7½, Otávio 6, Casemiro 6½, Horta 7½, Ben Yedder 6½, Trossard 6½, Mitoma 6 | | Swindon Town | 0 |
| | Half-time: | 0-0 | | Referee: | Atkinson 5½ | | Attendance: | 55,509 | | Possession: | 51%-49% | | Total shots: | 11-11 | | MoM: | Hrádecký |
| | 74 Ward-Prowse | | (5-3-2): Trafford 7½, Trippier 7½, Pinnock 7½, Dunk 7½, Branthwaite 7½, Zabarnyi 6½, Ward-Prowse 7½, Gibbs-White 7, Wilson 7, Gilmour 7, Johnson 7 | | FC Halifax | 0 |
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| | (4-3-3): Hrádecký 8, Ryerson 6½, Mæhle 7½, Christensen 7½, Andersen 6½, Svanberg 6, Kulusevski 7½, Højbjerg 6½, Haaland 6½, Ødegaard 7, Isak 6½ | | Tottenham Hotspur | 2 | 7og Skriniar, 68 Sterling | | Half-time: | 1-1 | | Referee: | Knight 5 | | Attendance: | 77,622 | | Possession: | 50%-50% | | Total shots: | 17-8 | | MoM: | Walker | | TV: | live |
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| | (4-4-2): Pickford 6½, White 8, Tomori 8, Zambo Anguissa 7, Stones 7, McKennie 7½, Walker 8, Maddison 7½, Bowen 6½, Rashford 7, Sterling 7½ | | Blackpool | 1 | 22 Rodri | | 24 Modric, 28 Rodri, 53 Reguilón | | (3-3-2-2): Ederson 6½, Carvajal 6½, Skriniar 7, Ronaldo 6, Rúben Dias 6, De Bruyne 7, Rúben Neves 5½, Van Dijk 6, Modric 6½, Reguilón 6½, Rodri 6 | | Tranmere Rovers | 1 | 14 Bailey | | Half-time: | 1-0 | | Referee: | Webb 6 | | Attendance: | 45,117 | | Possession: | 49%-51% | | Total shots: | 14-11 | | MoM: | Dier |
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| | (4-3-3): Ramsdale 7, Alexander-Arnold 6½, Colwill 7½, Ndidi 7, Dier 8, Gomez 6½, Madueke 7½, Pulisic 7, Mount 7, Bellingham 7, Bailey 7 | | Macclesfield FC | 1 | 64 Son |
| | (4-1-3-2): Maignan 7, Bah 6½, Alex Grimaldo 6½, Kamara 7, Romero 7, Süle 6½, Grifo 7½, Di María 7, Openda 6½, Sancet 7, Son 7 | | Round 22 | | Blackpool | 2 | 36 Modric, 70 Ronaldo | | Half-time: | 1-0 | | Referee: | Jones 6½ | | Attendance: | 56,964 | | Possession: | 45%-55% | | Total shots: | 11-12 | | MoM: | Alexander-Arnold |
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| | (3-3-2-2): Ederson 7½, Carvajal 7, Skriniar 5½, Ronaldo 6, Rúben Dias 7½, De Bruyne 6½, Rúben Neves 5½, Van Dijk 7, Modric 5½, Reguilón 5½, Rodri 6 | | Tranmere Rovers | 0 |
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| | (4-3-3): Ramsdale 7½, Alexander-Arnold 7½, Colwill 7, Ndidi 7, Dier 6½, Gomez 6½, Madueke 7½, Pulisic 7, Mount 7½, Bellingham 7, Bailey 6 | | Crewe Alexandra | 0 |
| | Half-time: | 0-0 | | Referee: | Haywood 5½ | | Attendance: | 35,454 | | Possession: | 37%-63% | | Total shots: | 8-11 | | MoM: | Zaniolo |
| | 21 Morata, 89 Richarlison | | (4-3-3): Leno 7, De Vrij 7½, Xhaka 7½, Richarlison 7, Hakimi 7½, Guerreiro 7, Morata 6½, William Carvalho 6½, Milinkovic-Savic 6½, Dani Olmo 7, Carrasco 6½ | | Crystal Palace | 0 |
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| | (4-3-3): Courtois 7, Cuadrado 7, Alex Sandro 7½, Zubimendi 7½, Varane 7½, Bonucci 7, Zaniolo 8, Palhinha 6, Joselu 6, Koke 6½, Mbappé 7 | | Macclesfield FC | 1 | 31 Sancet | | Half-time: | 1-0 | | Referee: | Troupkos 7½ | | Attendance: | 53,587 | | Possession: | 50%-50% | | Total shots: | 12-11 | | MoM: | Kamara |
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| | (4-1-3-2): Maignan 6, Bah 7½, Alex Grimaldo 7, Kamara 8, Romero 7½, Mario Hermoso 7½, Grifo 7½, Di María 7½, Openda 7, Sancet 6½, Son 7 | | Portsmouth | 1 | 56 Gündogan |
| | (4-4-2): Szczesny 7½, Digne 7, Gündogan 6½, Brozovic 7, Laporte 6½, Giménez 6½, Saka 6½, Cristante 6, Raphinha 5½, Kimmich 6½, Lukaku 6 | | Port Vale | 0 |
| | Half-time: | 0-0 | | Referee: | Graham 6½ | | Attendance: | 43,164 | | Possession: | 56%-44% | | Total shots: | 26-13 | | MoM: | Ben Yedder |
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| | (4-2-1-3): Sommer 7, Rodon 6½, Emerson Palmieri 7, Bonaventura 7½, Blind 7, Otávio 6½, Casemiro 7, Horta 6, Ben Yedder 8, Trossard 7, Mitoma 6½ | | Norwich City | 1 | 81 Núñez |
| | (4-4-2): Donnarumma 6½, Milenkovic 6½, Balde 6½, António Silva 6½, Diaby 6, García 7, Camavinga 7, Wirtz 7, Vitor Roque 6½, Kvaratskhelia 6, Núñez 6½ | | QPR | 3 | 23 Raum, 43 Paredes, 73 Raum | | Half-time: | 2-0 | | Referee: | Deadman 5½ | | Attendance: | 69,133 | | Possession: | 51%-49% | | Total shots: | 18-14 | | MoM: | Araújo |
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| | (4-3-3): Vicario 7½, João Mário 7, Raum 6½, Mac Allister 7, Le Normand 7, Schär 7, Paredes 6, Elmas 5½ (75 Aursnes 6), Vlasic 7 (82 Mukiele 6), Solanke 6, Adli 5½ | | Liverpool | 0 |
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| | (3-4-3): Neuer 7½, Araújo 8, Upamecano 6, Marcos Llorente 6½, Marquinhos 7, Zielinski 7, Brahim 7, Osimhen 6, Lewandowski 6½, Vinícius Júnior 6½, Coman 7 | | Swansea City | 2 | 5 Mané, 41 Dybala | | Half-time: | 2-1 | | Referee: | Pike 7 | | Attendance: | 71,685 | | Possession: | 48%-52% | | Total shots: | 12-16 | | MoM: | Szoboszlai |
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| | (3-4-3): Alisson 6, Hernández 6½, Alaba 8, Gabriel 7, João Cancelo 7½, Szoboszlai 8, Frimpong 7, Bernardo Silva 7½, Dybala 7½, Mané 6½, Benzema 6 | | Barnsley | 2 | 36 Longstaff, 76 Foden |
| | (4-4-2): Oblak 5½, Molina 6½, Maguire 6½, Rice 7, Longstaff 6½, Matviyenko 7, Elliott 6½, McGinn 6½, Beltrán 6½, Foden 6, Grealish 6½ | | Tottenham Hotspur | 2 | 8p Bowen, 9 Bowen | | Half-time: | 2-2 | | Referee: | Laws 7½ | | Attendance: | 68,526 | | Possession: | 47%-53% | | Total shots: | 16-11 | | MoM: | Christensen |
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| | (4-4-2): Pickford 6, White 7½, Tomori 7, Zambo Anguissa 7, Stones 7, McKennie 7½, Walker 6, Maddison 6, Bowen 7, Rashford 7, Sterling 6½ | | FC Halifax | 3 | 20 Kulusevski, 35 Isak, 56 Isak |
| | (4-3-3): Hrádecký 6, Ryerson 7, Mæhle 7, Christensen 7½, Andersen 7, Svanberg 6, Kulusevski 7, Højbjerg 6½, Haaland 7, Ødegaard 7, Isak 6½ | | Wolves | 3 | 6 Gabriel Jesus, 17 Vlahovic, 43 Gabriel Jesus | | Half-time: | 3-0 | | Referee: | Mathieson 7 | | Attendance: | 43,479 | | Possession: | 59%-41% | | Total shots: | 22-11 | | MoM: | Nübel |
| | 50 Gabriel Jesus | | (4-3-3): Nübel 8, Calabria 7, Nuno Mendes 7½, Vlahovic 6½, Nico Williams 6½, Tah 7½, Tapsoba 7, Verratti 6½, Gabriel Jesus 7, Kovacic 6½, Can 7½ | | Bristol Rovers | 0 |
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| | (4-3-3): Rui Patrício 7, Frankowski 6½, Tagliafico 6½, Rabiot 7½, Guehi 6½, Koulibaly 7 (83 Zeki 6), Danso 5½, Pedro Neto 6, Vargas 7, Lozano 5½, González 6½ (83 Vitinha 6) | | Wrexham | 1 | 10 Davies | | Half-time: | 1-1 | | Referee: | Shoebridge 6½ | | Attendance: | 66,215 | | Possession: | 44%-56% | | Total shots: | 13-10 | | MoM: | Akanji |
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| | (4-3-3): Ter Stegen 6, Ginter 7½, Hernández 7, Saliba 7, Bastoni 7, Locatelli 6, Chiesa 6, Kroos 7, Kane 7½, Goretzka 7, Davies 6½ | | Manchester United | 1 | 8 Pepê |
| | (4-3-3): Gulácsi 6½, Akanji 8, Mendy 7½, Lucas Paquetá 7, Rüdiger 7, Diego Carlos 6½, Salah 7, Brandt 6, Pepê 5½, Pellegrini 7 (81 Dembélé 6), Rodrygo 6½ |
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